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v3.25.1

Segment Information - Schedule of segment net loss and significant segment expenses (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023
Segment Reporting Information [Line Items] |  |
Net loss | $ (57,982) | $ (42,823)
Operating Segments [Member] |  |
Segment Reporting Information [Line Items] |  |
Non-controllable expenses | 8,733 | 3,988
Other income | 5,134 | 774
Net loss | 57,982 | 42,823
Operating Segments [Member] | Research and Development Expense [Member] |  |
Segment Reporting Information [Line Items] |  |
Total employee-related expenses | 11,135 | 10,351
Operating Segments [Member] | General and Administrative Expense [Member] |  |
Segment Reporting Information [Line Items] |  |
Total employee-related expenses | 5,553 | 3,240
Operating Segments [Member] | Research and Pre-clinical Expenses [Member] |  |
Segment Reporting Information [Line Items] |  |
Total external research and development expenses | 8,477 | 8,321
Operating Segments [Member] | Clinical and Development Expenses [Member] |  |
Segment Reporting Information [Line Items] |  |
Total external research and development expenses | 15,380 | 7,202
Operating Segments [Member] | Chemistry, Manufacturing, and Control Expenses [Member] |  |
Segment Reporting Information [Line Items] |  |
Total external research and development expenses | $ 3,570 | $ 8,947

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