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Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 12 Months Ended
Jun. 20, 2024
Jan. 30, 2024
Dec. 31, 2024
Dec. 31, 2023
Class of Stock [Line Items]        
Reclassification of euity upon conversion     $ 80,627  
Common stock, authorized     150,000,000 150,000,000
Common stock, par value     $ 0.0001 $ 0.0001
Common stock, issued     14,856,309 1,407,753
Common stock, outstanding     14,856,309 1,407,753
Common stock, voting rights     Holders of voting common stock are entitled to one vote per share.  
Common stock, dividends, per share, declared     $ 0  
SAFE [Member]        
Class of Stock [Line Items]        
Common stock, par value $ 12.4   $ 12.4  
Common stock, issued 2,752,216   2,752,216  
Subscription Agreement [Member]        
Class of Stock [Line Items]        
Sale of stock issue price per share $ 12.4 $ 12.4    
Proceeds from the issuance of common stock $ 96,600 $ 96,600    
AVROBIO [Member] | SAFE [Member]        
Class of Stock [Line Items]        
Common stock, issued     1,470,839  
Avorbio Common Stock [Member]        
Class of Stock [Line Items]        
Stock issued during the period shares new issues converted pursuant to reverse recapitalization     4,163,606  
Avorbio Common Stock [Member] | Subscription Agreement [Member]        
Class of Stock [Line Items]        
Stock issued during the period shares new issues converted pursuant to reverse recapitalization     4,163,606  
Preferred Stock [Member]        
Class of Stock [Line Items]        
Common stock issuable upon conversion     3,647,675  
Reclassification of euity upon conversion     $ 80,600  
Convertible Preferred stock, outstanding     0  
Convertible preferred stock authorized for issuance     0  
Convertible Preferred stock, issued     0  
Common Stock [Member]        
Class of Stock [Line Items]        
Common stock, authorized       11,947,558
Common stock, par value       $ 0.0001
Common stock, issued       2,634,246
Common stock, outstanding       2,634,246
Common stock, voting rights       Holders of common stock were entitled to one vote for each share of common stock
Undesignated Preferred Stock [Member]        
Class of Stock [Line Items]        
Convertible Preferred stock, outstanding     0  
Convertible Preferred stock, issued     0  
Restricted Common Stock [Member]        
Class of Stock [Line Items]        
Common stock, issued       2,634,246
Common stock, outstanding       2,634,246
Unrestricted Common Stock [Member]        
Class of Stock [Line Items]        
Convertible Preferred stock, authorized     10,000,000  
Common stock, outstanding       2,598,752