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Summary of significant accounting policies (Tables) | 9 Months Ended
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Sep. 30, 2018
Summary of Significant Accounting Policies |
Schedule of cash, cash equivalents, and restricted cash | The following table presents cash, cash equivalents and restricted cash as reported on the condensed consolidated balance sheets that equal the total amounts on the condensed consolidated statements of cash flows (in thousands):
|  | September 30,
|  | 2018 |  | 2017
Cash and cash equivalents |  | $ | 111,701 |  | $ | 86,542
Restricted cash included in "Restricted cash and other non-current assets" |  |  | 1,619 |  |  | 1,619
Total |  | $ | 113,320 |  | $ | 88,161
Schedule of contract assets and liabilities | The following table presents changes in the Company’s deferred revenue balance as of January 1, 2018 resulting from adoption of ASC 606 (in thousands):
| Balance at December 31, 2017 |  | Adjustments |  | Balance at January 1, 2018
Contract liabilities: |  |  |  |  |  |  |  |
Deferred revenue | $ | (107,963) |  | $ | (474) |  | $ | (108,437)
Schedule of accounts receivable and contract liabilities | The following table presents changes in the Company’s accounts receivable and contract liabilities for the nine months ended September 30, 2018 (in thousands):
For the nine months ended September 30, 2018 | Balance at December 31, 2017 |  | Additions |  | Deductions |  | Balance at September 30, 2018
Accounts receivable | $ | 679 |  | $ | 1,189 |  | $ | (1,825) |  | $ | 43
Contract liabilities: |  |  |  |  |  |  |  |  |  |  |
Deferred revenue | $ | (107,963) |  | $ | (9,986) |  | $ | 5,124 |  | $ | (112,825)
Schedule of change in contract assets and contract liabilities | During the three and nine months ended September 30, 2018, the Company recognized revenue as a result of the following (in thousands):
|  | Three Months Ended |  |  | Nine Months Ended
Revenue recognized in the period from: | September 30, 2018
Amounts included in deferred revenue at the beginning of the period | $ | 687 |  | $ | 4,457
Performance obligations satisfied in previous periods | $ | (1,255) |  | $ | 1,311
Schedule of financial statement line items for comparability purposes | The Company has included the following financial statement line items for comparability purposes as of and for the three and nine months ended September 30, 2018 (in thousands):
|  | Three Months Ended September 30, 2018
| As reported under Topic 606 |  | Balances without adoption of ASC 606 |  | Effect of Change
Collaboration and other research and development revenues | $ | 14,519 |  | $ | 18,974 |  | $ | (4,455)
Operating loss | $ | (16,258) |  | $ | (11,803) |  | $ | (4,455)
Net loss attributable to common stockholders | $ | (15,238) |  | $ | (10,783) |  | $ | (4,455)
Net loss per share attributable to common stockholders, basic and diluted | $ | (0.32) |  | $ | (0.23) |  | $ | (0.09)
|  | Nine Months Ended September 30, 2018
| As reported under Topic 606 |  | Balances without adoption of ASC 606 |  | Effect of Change
Collaboration and other research and development revenues | $ | 25,818 |  | $ | 28,933 |  | $ | (3,115)
Operating loss | $ | (87,474) |  | $ | (84,359) |  | $ | (3,115)
Net loss attributable to common stockholders | $ | (84,899) |  | $ | (81,784) |  | $ | (3,115)
Net loss per share attributable to common stockholders, basic and diluted | $ | (1.81) |  | $ | (1.75) |  | $ | (0.07)
|  | As of September 30, 2018
| As reported under Topic 606 |  | Balances without adoption of ASC 606 |  | Effect of Change
Deferred revenue, current | $ | 8,725 |  | $ | 13,374 |  | $ | (4,649)
Deferred revenue, net of current portion | $ | 104,100 |  | $ | 86,085 |  | $ | 18,015
Accumulated deficit | $ | (391,223) |  | $ | (388,108) |  | $ | (3,115)

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