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Nature of Business (Details) - USD ($) $ in Thousands | 1 Months Ended |
--- | --- | ---
Jan. 31, 2018 | Dec. 31, 2017 | Mar. 31, 2017 | Feb. 29, 2016 | Sep. 30, 2018
Liquidity |  |  |  |  |
Accumulated deficit |  | $ (305,850) |  |  | $ (391,223)
Initial Public Offering |  |  |  |  |
Liquidity |  |  |  |  |
Aggregate net proceeds |  |  |  | $ 97,500 |
2017 March Offering |  |  |  |  |
Liquidity |  |  |  |  |
Aggregate net proceeds |  |  | $ 96,700 |  |
2017 December Offering |  |  |  |  |
Liquidity |  |  |  |  |
Aggregate net proceeds |  | $ 57,200 |  |  |
2018 January Offerings |  |  |  |  |
Liquidity |  |  |  |  |
Aggregate net proceeds | $ 48,500 |  |  |  |

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