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Stock-based Compensation - Restricted Stock and Stock Options (Details) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017	Dec. 31, 2014
Changes in unvested restricted stock
Unvested restricted common stock, beginning of period (in shares)			513,225
Vested (in shares)			(225,225)
Unvested restricted common stock, end of period(in shares)	288,000		288,000		513,225
Weighted Average Grant Date Fair Value
Balance, beginning of period			$ 18.70
Vested (in dollars per share)			6.75
Balance, ending of period	$ 28.05		$ 28.05		$ 18.70
Changes in unvested stock options
Compensation expense	$ 6,699	$ 4,468	$ 20,251	$ 15,287
Options exercised prior to vesting (in shares)						75,304
Options exercised prior to vesting , exercise price per share						$ 0.03
Outstanding, beginning of period (in shares)			4,372,136
Granted (in shares)			1,643,185
Exercised (in shares)			(634,331)
Cancelled (in shares)			(558,504)
Outstanding, end of period (in shares)	4,822,486		4,822,486		4,372,136
Exercisable (in shares)	1,881,620		1,881,620
Outstanding, beginning of period (in dollars per share)			$ 17.28
Granted (in dollars per share)			36.29
Exercised (in dollars per share)			13.73
Cancelled (in dollars per share)			24.88
Outstanding, end of period (in dollars per share)	$ 23.38		23.38		$ 17.28
Exercisable (in dollar per share)	$ 17.65		$ 17.65
Remaining contractual life			8 years 2 months 12 days		8 years 6 months
Exercisable, remaining contractual life			7 years 6 months
Aggregate intrinsic value	$ 48,750		$ 48,750		$ 60,591
Exercisable, aggregated intrinsic value	$ 28,201		$ 28,201
Unvested stock options (in shares)	0		0		4,572
Employees and directors
Changes in unvested stock options
Compensation expense			$ 14,900	$ 9,100
Unrecognized stock-based compensation expense	$ 51,800		$ 51,800
Weighted average fair value of options granted (per share)			$ 25.65	$ 16.71
Restricted Stock | Employees
Changes in unvested stock options
Compensation expense			$ 0
Unrecognized stock-based compensation expense	0		0
Restricted Stock | Non-employees
Changes in unvested stock options
Compensation expense			1,900
Unrecognized stock-based compensation expense	$ 9,000		$ 9,000

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