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Common Stock - Stock Incentive Plan (Details) | 1 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | ---
Jan. 31, 2021 shares | Nov. 30, 2020 shares | Dec. 31, 2020 item $ / shares shares | Dec. 31, 2019 shares | Jul. 31, 2015 shares | Sep. 30, 2013 shares
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 12,030,284 | 10,433,255 |  |
Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Options granted (in shares) |  |  | 1,721,748 |  |  |
Restricted Stock |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares granted |  |  | 364,549 |  |  |
Issued (in dollars per share) | $ / shares |  |  | $ 29.57 |  |  |
2013 Plan |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares authorized |  |  |  |  |  | 1,057,692
Shares reserved for future awards |  |  |  |  | 6,317,769 |
2013 Plan | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Expiration period |  |  | 10 years |  |  |
2013 Plan | Performance based awards |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Number of awards with performance vesting criteria | item |  |  | 1 |  |  |
2015 Plan |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Increase to number of shares authorized | 2,507,552 |  |  |  |  |
2015 Employee Stock Purchase Plan |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Increase to number of shares authorized | 626,888 |  |  |  |  |
Shares reserved for future awards |  |  | 2,137,127 | 1,630,199 |  |
Maximum | 2013 Plan | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Vesting period |  |  | 4 years |  |  |
Maximum | 2015 Plan |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 2,923,076 |  |  |
Percent of shares outstanding reserved for future awards (as a percent) |  |  | 4.00% |  |  |
Maximum | 2015 Employee Stock Purchase Plan |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 769,230 |  |  |
Percent of shares outstanding reserved for future awards (as a percent) |  |  | 1.00% |  |  |
Minimum | 2013 Plan | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Vesting period |  |  | 1 year |  |  |
Chief Medical Officer | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Options granted (in shares) |  | 120,000 |  |  |  |
Chief Medical Officer | Restricted Stock Units (RSUs) |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares granted |  | 20,000 |  |  |  |
Common Stock | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 280,000 | 175,000 |  |
Common Stock | 2013 Plan | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 174,362 | 312,342 |  |
Common Stock | 2015 Plan |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 5,599,450 | 4,061,357 |  |
Common Stock | 2015 Plan | Stock options |  |  |  |  |  |
Stock-based compensation disclosures |  |  |  |  |  |
Shares reserved for future awards |  |  | 3,839,345 | 4,254,357 |  |

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