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Summary of significant accounting policies (Tables) | 12 Months Ended
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Dec. 31, 2020
Schedule of cash, cash equivalents, and restricted cash | The following table presents cash, cash equivalents, and restricted cash as reported on the consolidated balance sheets that equal the total amounts on the consolidated statements of cash flows (in thousands): ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ | ​ | 2020 | ​ | 2019
Cash and cash equivalents | ​ | $ | 511,774 | ​ | $ | 238,183
Restricted cash included in "Restricted cash and other non-current assets" | ​ | ​ | 3,877 | ​ | ​ | 1,619
Total cash, cash equivalents, and restricted cash | ​ | $ | 515,651 | ​ | $ | 239,802
Schedule of estimated useful lives of property, plant and equipment |
​ | ​ | ​ | ​
Asset: |  | Estimated Useful life |
Lab equipment |  | 5 years | ​
Computer equipment and software |  | 3 years | ​
Furniture and equipment |  | 5 years | ​
Leasehold improvements |  | Shorter of useful life or remaining lease term | ​
ASU 2016-02 |
Schedule of financial statement line items for comparability purposes |
​ | ​ | ​
​ | As of
​ | January 1, 2019
Property and equipment, net | $ | 32,627
Other current liabilities | $ | (1,014)
Construction financing lease obligation, net of current portion | $ | (32,417)
Accumulated deficit | $ | 803

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