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Subsequent Events (Details) - USD ($) $ in Thousands	1 Months Ended				12 Months Ended
	Feb. 28, 2021	Jan. 31, 2021	Jun. 30, 2020	Jun. 30, 2018	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Subsequent Events
Number of common stock issued			6,900,000
Proceeds from offering of common stock, net of issuance costs			$ 203,700		$ 203,726	$ 116,341	$ 76,789
Overallotment Option
Subsequent Events
Number of common stock issued			900,000
Broad | Sponsored Research Agreement
Subsequent Events
Stock issued to licensors				330,617
Market capitalization					$ 2,500,000
Broad, Massachusetts Institute of Technology, or MIT, and Harvard (Institutions) | Cas9-II License Agreement
Subsequent Events
Market capitalization								$ 1,000,000
Subsequent Event | Public Offering
Subsequent Events
Number of common stock issued		3,500,000
Proceeds from offering of common stock, net of issuance costs		$ 216,900
Subsequent Event | Overallotment Option
Subsequent Events
Number of stock upon exercise of option	525,000
Proceeds from offering of common stock, net of issuance costs	$ 32,600
Subsequent Event | Broad | Sponsored Research Agreement
Subsequent Events
Stock issued to licensors		303,599
Subsequent Event | Broad, Massachusetts Institute of Technology, or MIT, and Harvard (Institutions) | Cas9-II License Agreement
Subsequent Events
Market capitalization		$ 3,000,000

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