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Stock-based Compensation - Expense (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Stock-based compensation disclosures |  |  |  |
Compensation expense | $ 5,881 | $ 10,012 | $ 23,930 | $ 35,742
Research and development |  |  |  |
Stock-based compensation disclosures |  |  |  |
Compensation expense | 3,045 | 4,552 | 9,803 | 12,689
General and administrative |  |  |  |
Stock-based compensation disclosures |  |  |  |
Compensation expense | $ 2,836 | $ 5,460 | $ 14,127 | $ 23,053

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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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