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Stock-based Compensation (Tables)

6 Months Ended

Jun. 30, 2025

Share-Based Payment Arrangement [Abstract]

Schedule of Stock-Based Compensation Expense

Total compensation cost recognized for all stock-based compensation awards in the condensed consolidated statements of operations was as follows (in thousands):

			Three Months Ended June 30,												Six Months Ended June 30,
			2025						2024						2025						2024
Research and development			$	863					$	2,125					$	1,770					$	5,033
General and administrative			1,801						2,885						3,873						7,562
Total stock-based compensation expense			$	2,664					$	5,010					$	5,643					$	12,595

Schedule of Changes in Unvested Restricted Stock

The following is a summary of restricted stock unit awards activity for the six months ended June 30, 2025:

			Shares						Weighted Average Grant Date Fair Value Per Share
Unvested restricted stock unit awards as of December 31, 2024			2,326,523						$	9.78
Issued			1,560						$	1.26
Vested			(371,498)						$	10.42
Forfeited			(1,033,046)						$	10.11
Unvested restricted stock unit awards as of June 30, 2025			923,539						$	9.15

Schedule of Stock Option Activity

The following is a summary of stock option activity for the six months ended June 30, 2025:

			Shares						Weighted Average Exercise Price						Remaining Contractual Life (years)						Aggregate Intrinsic Value
Outstanding at December 31, 2024			7,656,010						$	14.70					7.19						$	—
Granted			5,581,038						$	1.71
Exercised			—						$	—
Cancelled			(2,791,231)						$	11.85
Outstanding at June 30, 2025			10,445,817						$	8.54					7.71						$	2,505
Exercisable at June 30, 2025			4,026,696						$	16.59					5.23						$	120

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Tabular disclosure of the changes in outstanding nonvested restricted stock shares.

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-Name Accounting Standards Codification
-Section 50
-Subparagraph (c)
-Paragraph 2
-SubTopic 10
-Topic 718
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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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-SubTopic 10
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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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