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Segments - Schedule of Segment Reporting Information, by Segment (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended 7 Months Ended
Jun. 30, 2025
Mar. 31, 2025
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Segment Reporting Information [Line Items]              
Collaboration and other research and development revenues $ 3,578   $ 513   $ 8,236 $ 1,649  
Operating expenses:              
Stock-based compensation expenses 2,664   5,010   5,643 12,595  
Total operating expenses 55,122   72,416   135,943 140,542  
Operating loss (51,544)   (71,903)   (127,707) (138,893)  
Other (expense) income, net:              
Other (expense) income, net (1,758)   (1)   (2,183) 5  
Interest related to sale of future revenues (2,020)   0   (4,236) 0  
Interest income, net 2,087   4,297   4,803 9,331  
Total other (expense) income, net (1,691)   4,296   (1,616) 9,336  
Net loss (53,235) $ (76,088) (67,607) $ (61,950) (129,323) (129,557)  
Restructuring and impairment charges             $ 79,167
Reportable Segment              
Segment Reporting Information [Line Items]              
Collaboration and other research and development revenues 3,578   513   8,236 1,649  
Operating expenses:              
Total operating expenses 55,122   72,416   135,943 140,542  
Operating loss (51,544)   (71,903)   (127,707) (138,893)  
Other (expense) income, net:              
Other (expense) income, net (1,758)   (1)   (2,183) 5  
Interest income, net 2,087   4,297   4,803 9,331  
Total other (expense) income, net (1,691)   4,296   (1,616) 9,336  
Net loss (53,235)   (67,607)   (129,323) (129,557)  
Research and development              
Operating expenses:              
Stock-based compensation expenses 863   2,125   1,770 5,033  
Research and development | Reportable Segment              
Operating expenses:              
Employee related expenses 8,575   13,661   22,742 27,344  
External research and development expenses 25,111   27,025   60,466 44,613  
Facility expenses 4,581   7,370   13,974 12,589  
Stock-based compensation expenses 863   2,125   1,770 5,033  
Sublicense and license fees 95   857   112 6,753  
Other expenses 1,787   3,172   7,785 6,665  
Other (expense) income, net:              
Restructuring and impairment charges 24,830   64,075        
General and administrative              
Operating expenses:              
Stock-based compensation expenses 1,801   2,885   3,873 7,562  
General and administrative | Reportable Segment              
Operating expenses:              
Employee related expenses 3,436   4,800   8,541 9,690  
Facility expenses 1,941   2,783   4,762 5,695  
Stock-based compensation expenses 1,801   2,885   3,873 7,562  
Professional service expenses 3,711   3,893   6,151 6,808  
Intellectual property and patent related fees 3,221   3,845   $ 5,767 $ 7,790  
Other (expense) income, net:              
Restructuring and impairment charges $ 1,251   $ 2,860