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Property and Equipment, net (Details) - USD ($) $ in Thousands	Sep. 30, 2025	Dec. 31, 2024
Property and equipment, net
Total property and equipment	$ 31,834	$ 46,145
Less: accumulated depreciation	(27,547)	(31,648)
Property and equipment, net	4,287	14,497
Laboratory and manufacturing equipment
Property and equipment, net
Total property and equipment	21,418	29,128
Leasehold improvements
Property and equipment, net
Total property and equipment	8,403	11,749
Computer equipment
Property and equipment, net
Total property and equipment	1,399	1,490
Construction-in-progress
Property and equipment, net
Total property and equipment	79	827
Furniture and office equipment
Property and equipment, net
Total property and equipment	191	264
Software
Property and equipment, net
Total property and equipment	$ 344	$ 2,687

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Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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