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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Cash flow from operating activities    
Net loss $ (154,440) $ (191,698)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 7,871 17,397
Depreciation 4,472 4,428
Loss on disposal of fixed assets 2,193 139
Net accretion of discounts on marketable securities (902) (4,922)
Interest related to sale of future revenues 6,635 0
Impairment of held for sale assets 3,724 0
Other non-cash items (390) (415)
Changes in operating assets and liabilities:    
Accounts receivable 8,136 10,061
Prepaid expenses and other current assets 175 1,607
Right-of-use assets 10,122 (2,048)
Other non-current assets 1,026 3,306
Accounts payable (2,330) 4,713
Accrued expenses 1,728 (5,523)
Accrued interest on sale of future revenues (2,128) 0
Deferred revenue (6,221) 0
Operating lease liabilities (10,531) 1,952
Other non-current liabilities 2,006 1,481
Net cash used in operating activities (128,854) (159,522)
Cash flow from investing activities    
Purchases of property and equipment (547) (8,286)
Proceeds from the sale of equipment 151 0
Purchases of marketable securities 0 (86,221)
Proceeds from maturities of marketable securities 139,006 225,695
Net cash provided by investing activities 138,610 131,188
Cash flow from financing activities    
Repayment on sale of future revenues (2,872) 0
Proceeds from issuance of common stock from at-the-market equity offering, net 25,767 0
Proceeds from exercise of stock options 21 192
Proceeds from issuance of common stock under employee stock purchase plan 228 322
Net cash provided by financing activities 23,144 514
Net increase (decrease) in cash, cash equivalents, and restricted cash 32,900 (27,820)
Cash, cash equivalents, and restricted cash, beginning of period 135,418 127,529
Cash, cash equivalents, and restricted cash, end of period 168,318 99,709
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]    
Cash and cash equivalents, end of period 165,648 95,832
Restricted cash [1] 2,670 3,877
Cash, cash equivalents, and restricted cash, end of period 168,318 99,709
Supplemental disclosure of cash and non-cash activities:    
Fixed asset additions included in accounts payable and accrued expenses 0 134
Cash paid in connection with operating lease liabilities 12,992 12,565
Remeasurement of operating lease liabilities and right-of-use assets due to lease modification 766 794
Commencement of right-of-use asset 0 7,844
Modification of right-of-use asset 0 1,954
Non-cash termination of right-of-use asset $ 4,849 $ 0
[1]
1 As of September 30, 2025 and September 30, 2024, restricted cash of $2,670 and $3,877 was included in Restricted cash and other non-current assets on the Consolidated Balance Sheet, respectively.