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Convertible loan notes - Summary of Interest-bearing Loans and Borrowings (Detail) - GBP (£)
£ in Thousands
Jun. 30, 2022
Dec. 31, 2021
Disclosure of detailed information about borrowings [abstract]    
Novartis Loan Note £ 4,094 £ 3,771
Loan Notes – private placement 11,858 10,613
Total 15,952 14,384
Current £ 15,952  
Non-current   £ 14,384