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Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Revenue:      
Total revenue $ 21,098 $ 21,219 $ 27,508
Type of Revenue [Extensible List]   alec:CollaborationRevenueMember alec:CollaborationRevenueMember
Grant revenue     $ 169
Total revenue 21,098 $ 21,219 27,677
Operating expenses:      
Research and development 156,869 100,528 73,031
General and administrative 59,403 35,095 11,934
Total operating expenses 216,272 135,623 84,965
Loss from operations (195,174) (114,404) (57,288)
Other income, net 4,946 9,019 5,040
Net loss (190,228) (105,385) (52,248)
Unrealized gain (loss) on marketable securities 472 184 (42)
Comprehensive loss $ (189,756) $ (105,201) $ (52,290)
Net loss per share, basic and diluted $ (2.45) $ (1.71) $ (4.62)
Shares used in computing net loss per share, basic and diluted 77,758,806 61,734,492 11,302,788