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Stock-based Compensation - Summary of Recognized Stock-Based Compensation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total stock-based compensation $ 46,146 $ 40,785 $ 30,522
Research and Development      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total stock-based compensation 24,895 21,443 14,980
General and Administrative      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total stock-based compensation $ 21,251 $ 19,342 $ 15,542