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Summary of Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2026

Accounting Policies [Abstract]

Schedule of Reconciliation of Cash, Cash Equivalents, and Restricted Cash

The following table provides a reconciliation of cash, cash equivalents, and restricted cash reported within the condensed consolidated balance sheets that sum to the total of the same amounts shown in the condensed consolidated statements of cash flows:

		Three Months Ended  March 31,
		2026				2025
		(In thousands)
Cash and cash equivalents		$	76,962			$	37,973
Restricted cash			1,846				1,846
Total cash, cash equivalents, and restricted cash		$	78,808			$	39,819

Summary of Segment Profit or Loss Including Significant Segment Expenses

The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):

		Three Months Ended March 31,
		2026				2025
Collaboration revenue		$	1,046			$	3,674
Less:
Compensation and benefits			8,248				16,557
Lab expenses and outside research services			3,447				3,224
Clinical supply costs			1,379				3,074
Clinical trials			3,384				7,013
Support functions			6,300				8,286
Other segment expenses(a)			3,207				10,215
Total operating expenses			25,965				48,369
Loss from operations			(24,919	)			(44,695	)
Other income, net			1,989				4,224
Segment and consolidated loss before income taxes		$	(22,930	)		$	(40,471	)

(a) Other segment expenses include consultants & contractor expense, contra-R&D expense for GSK collaboration, depreciation expense, impairment loss, restructuring expense, and stock-based compensation expense.

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Tabular disclosure of cash and cash equivalents restricted as to withdrawal or usage.

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Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

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