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v3.26.1

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2026 | Jun. 30, 2025
Cash flows from operating activities: |  |
Net loss | $ (45,920) | $ (70,995)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 2,130 | 3,313
Stock-based compensation | 5,518 | 15,413
Amortization of premiums and accretion of discounts on marketable securities | (1,170) | (3,785)
Amortization of right-of-use assets | 2,003 | 1,757
Amortization of debt discount and debt issuance costs | 159 | 140
Impairment of right-of-use assets and leasehold improvements | 0 | 1,151
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 3,139 | (478)
Other assets | 33 | 50
Accounts payable | 592 | 2
Accrued liabilities and accrued clinical supply costs | (13,791) | (16,507)
Payable to collaboration partner | (13,572) | 693
Deferred revenue | (4,366) | (11,548)
Refund liability to collaboration partner | (15,438) | (26,063)
Lease liabilities | (3,634) | (3,182)
Other long-term liabilities | 287 | 210
Net cash used in operating activities | (84,030) | (109,829)
Cash flows from investing activities: |  |
Purchase of property and equipment | (149) | (30)
Purchase of marketable securities | (79,656) | (131,879)
Maturities of marketable securities | 157,873 | 250,385
Sale of marketable securities | 0 | 2,981
Net cash provided by investing activities | 78,068 | 121,457
Cash flows from financing activities: |  |
Proceeds from the exercise of options to purchase common stock | 27 | 0
Purchase of common stock under employee stock purchase plan | 48 | 122
Net cash provided by financing activities | 75 | 122
Net increase (decrease) in cash, cash equivalents, and restricted cash | (5,887) | 11,750
Cash, cash equivalents, and restricted cash at beginning of period | 67,648 | 34,867
Cash, cash equivalents, and restricted cash at end of period | 61,761 | 46,617
Supplemental Disclosures: |  |
Cash paid for interest | $ 404 | $ 216

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