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Condensed Consolidated Statements of Cash Flows - CHF (SFr)
SFr in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Operating activities      
Loss for the period SFr (70,753) SFr (72,996) SFr (61,921)
Adjustments to reconcile net loss for the period to net cash flows:      
Depreciation of property, plant and equipment 1,793 1,897 1,535
Depreciation of right-of-use assets 566 509 432
Finance (income)/expense, net (559) (6,769) 376
Share-based compensation expense 3,330 4,126 4,088
Change in net employee defined benefit liability 541 590 705
Interest expense 355 573 175
(Gain)/loss on sale of fixed assets 0 13 (64)
Changes in working capital:      
(Increase)/decrease in prepaid expenses (1,718) 791 (1,304)
Decrease/(increase) in accrued income 567 594 (507)
Decrease/(increase) in other current receivables 36 (99) (25)
(Decrease)/increase in accrued expenses (6,114) 5,214 (757)
(Decrease)/increase in deferred income (130) 425 (4,157)
(Decrease)/increase in trade and other payables (1,073) (84) 2,177
Cash used in operating activities (73,159) (65,216) (59,247)
Interest received 69 0 78
Interest paid (470) (465) (339)
Finance expenses paid (8) (8) (9)
Net cash flows used in operating activities (73,568) (65,689) (59,517)
Investing activities      
Short-term financial assets, net 25,000 (51,000) 30,000
Purchases of property, plant and equipment (1,239) (2,635) (1,706)
Proceeds from sale of property, plant and equipment 0 0 64
Rental deposits 2 (29) (29)
Net cash flows provided by/(used in) investing activities 23,763 (53,664) 28,329
Financing activities      
Proceeds from issuance of convertible loan 0 23,463 0
Transaction costs on issuance of shares 0 (6) 0
Proceeds from sale of treasury shares in public offerings, net of underwriting fees and transaction costs (8)    
Proceeds from issuance of treasury shares, net of underwriting fees and transaction costs 0 12,121 100
Proceeds from issuance of common shares - asset acquisition, net of transaction costs 0 4,599 0
Proceeds from issuance of common shares - option plan, net of transaction costs 7 1,082 143
Principal payments of lease obligations (569) (513) (432)
Transaction costs associated with issuance of shares in relation to asset acquisition previously recorded in Accrued expenses (776)    
Repayment of short-term financing obligation 0 0 (514)
Payment for the issuance of treasury shares 0 0 (100)
Net cash flows (used in)/provided by financing activities (1,346) 40,746 (803)
Net decrease in cash and cash equivalents (51,151) (78,607) (31,991)
Cash and cash equivalents at beginning of period 82,216 160,893 193,587
Exchange gain on cash and cash equivalents 521 (70) (703)
Cash and cash equivalents at end of the period 31,586 82,216 160,893
Supplemental non-cash activity      
Capital expenditures in Trade and other payables or Accrued expenses 0 303 328
Issuance of shares for purchase of IPR&D asset in asset acquisition 0 50,416 0
Transaction costs associated with issuance of shares in relation to the asset acquisition recorded in Accrued expenses 0 776 0
Settlement of convertible notes recorded within Shareholders' equity SFr 0 SFr 16,920 SFr 0