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Expenses by category (Details)
SFr in Thousands
 12 Months Ended
Dec. 31, 2022
CHF (SFr)
employee
Dec. 31, 2021
CHF (SFr)
employee
Dec. 31, 2020
CHF (SFr)
employee
Disclosure of detailed information about borrowings [line items]      
Operating expenses SFr 74,782 SFr 79,010 SFr 76,691
Research and development expenses 60,336 62,282 59,487
General and administrative expenses 15,789 17,910 18,557
Financial result, net [Abstract]      
Financial income 69 6,485 78
Financial expense (355) (581) (184)
Exchange differences 393 113 (555)
Finance result, net 107 6,017 (661)
Gains on conversion features related to convertible notes   6,500  
Research and development expenses      
Disclosure of detailed information about borrowings [line items]      
Operating expenses 41,166 44,289 43,787
Payroll expenses 17,548 16,465 14,424
Share-based compensation 1,622 1,528 1,276
Total expenses by category SFr 60,336 SFr 62,282 SFr 59,487
Average number of employees | employee 122.4 108.6 115.3
General and administrative expenses      
Disclosure of detailed information about borrowings [line items]      
Operating expenses SFr 6,207 SFr 7,031 SFr 7,471
Payroll expenses 7,874 8,281 8,274
Share-based compensation 1,708 2,598 2,812
Total expenses by category SFr 15,789 SFr 17,910 SFr 18,557
Average number of employees | employee 22.5 27.3 26.7