<SEC-DOCUMENT>0001683168-21-006027.txt : 20211130
<SEC-HEADER>0001683168-21-006027.hdr.sgml : 20211130
<ACCEPTANCE-DATETIME>20211130162515
ACCESSION NUMBER:		0001683168-21-006027
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20211130
FILED AS OF DATE:		20211130
DATE AS OF CHANGE:		20211130

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ralph David L.
		CENTRAL INDEX KEY:			0001543736

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32046
		FILM NUMBER:		211459983

	MAIL ADDRESS:	
		STREET 1:		42505 10TH STREET WEST
		CITY:			LANCASTER
		STATE:			CA
		ZIP:			93534

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Simulations Plus, Inc.
		CENTRAL INDEX KEY:			0001023459
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMPUTER INTEGRATED SYSTEMS DESIGN [7373]
		IRS NUMBER:				954595609
		FISCAL YEAR END:			0831

	BUSINESS ADDRESS:	
		STREET 1:		42505 10TH STREET WEST
		CITY:			LANCASTER
		STATE:			CA
		ZIP:			93534-7059
		BUSINESS PHONE:		661-723-7723

	MAIL ADDRESS:	
		STREET 1:		42505 10TH STREET WEST
		CITY:			LANCASTER
		STATE:			CA
		ZIP:			93534-7059

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SIMULATIONS PLUS INC
		DATE OF NAME CHANGE:	19960923
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>ownership.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-11-30</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001023459</issuerCik>
        <issuerName>Simulations Plus, Inc.</issuerName>
        <issuerTradingSymbol>SLP</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001543736</rptOwnerCik>
            <rptOwnerName>Ralph David L.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>42505 10TH STREET WEST</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>LANCASTER</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>93534</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <remarks>The reporting person resigned as director of the issuer effective November 30, 2021. As a result, the reporting person is no longer subject to Section 16 in connection with his transactions in the equity securities of the issuer, and therefore will no longer report any such transactions on Form 4 or Form 5.</remarks>

    <ownerSignature>
        <signatureName>/s/ David Ralph</signatureName>
        <signatureDate>2021-11-30</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
