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Income Taxes - Schedule of Reconciliation of Income Tax Expense Applying Statutory Federal Income Rate (Detail) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024
Amount |  |  |
Tax at statutory rates |  | $ (12,094,000) | $ (4,323,000)
State and local income taxes, net of federal income tax effect | [1] | $ (136,000) | $ (50,000)
Effective Income Tax Rate Reconciliation, State and Local Jurisdiction, Contribution Greater than 50 Percent, Tax Effect [Extensible Enumeration] |  | CALIFORNIA | CALIFORNIA
Effects of changes in tax laws or rates in the current period |  | $ 0 | $ 0
Research and development credits |  | (5,286,000) | (2,986,000)
Change in valuation allowance |  | 15,766,000 | 6,146,000
Stock-based compensation expense |  | 221,000 | 84,000
Research expenses |  | 0 | 347,000
Executive compensation |  | 138,000 | 0
Permanent differences |  | 20,000 | (14,000)
Changes in unrecognized tax benefits |  | 1,371,000 | 796,000
Other, net |  | 0 | 0
Total income tax expense (benefit) |  | $ 0 | $ 0
Percent |  |  |
Tax at statutory rates |  | 21.00% | 21.00%
State and local income taxes, net of federal income tax effect | [1] | 0.20% | 0.20%
Effects of changes in tax laws or rates in the current period |  |  |
Research and development credits |  | 9.20% | 14.50%
Change in valuation allowance |  | (27.40%) | (29.80%)
Stock-based compensation expense |  | (0.40%) | (0.40%)
Research expenses |  |  | (1.70%)
Executive compensation |  | (0.20%) |
Permanent differences |  |  | 0.10%
Changes in unrecognized tax benefits |  | (2.40%) | (3.90%)
Other, net |  |  |
Total income tax expense (benefit) |  |  |
[1] | State income taxes in California comprise the majority (greater than 50%) of the tax effect in this category.

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