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Income Taxes - Schedule of Reconciliation of Income Tax Expense Applying Statutory Federal Income Rate (Detail) - USD ($)
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Amount    
Tax at statutory rates $ (12,094,000) $ (4,323,000)
State and local income taxes, net of federal income tax effect [1] $ (136,000) $ (50,000)
Effective Income Tax Rate Reconciliation, State and Local Jurisdiction, Contribution Greater than 50 Percent, Tax Effect [Extensible Enumeration] CALIFORNIA CALIFORNIA
Effects of changes in tax laws or rates in the current period $ 0 $ 0
Research and development credits (5,286,000) (2,986,000)
Change in valuation allowance 15,766,000 6,146,000
Stock-based compensation expense 221,000 84,000
Research expenses 0 347,000
Executive compensation 138,000 0
Permanent differences 20,000 (14,000)
Changes in unrecognized tax benefits 1,371,000 796,000
Other, net 0 0
Total income tax expense (benefit) $ 0 $ 0
Percent    
Tax at statutory rates 21.00% 21.00%
State and local income taxes, net of federal income tax effect [1] 0.20% 0.20%
Effects of changes in tax laws or rates in the current period
Research and development credits 9.20% 14.50%
Change in valuation allowance (27.40%) (29.80%)
Stock-based compensation expense (0.40%) (0.40%)
Research expenses (1.70%)
Executive compensation (0.20%)
Permanent differences 0.10%
Changes in unrecognized tax benefits (2.40%) (3.90%)
Other, net
Total income tax expense (benefit)
[1] State income taxes in California comprise the majority (greater than 50%) of the tax effect in this category.