    <SEC-DOCUMENT>0001193125-21-227369-index.html : 20210728
    <SEC-HEADER>0001193125-21-227369.hdr.sgml : 20210728
    <ACCEPTANCE-DATETIME>20210728160228
    ACCESSION NUMBER:		0001193125-21-227369
    CONFORMED SUBMISSION TYPE:	424B4
    PUBLIC DOCUMENT COUNT:		29
    FILED AS OF DATE:		20210728
    DATE AS OF CHANGE:		20210728

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Candel Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0001841387
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		IRS NUMBER:				522214851
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		424B4
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-257444
    		FILM NUMBER:		211122525

    	BUSINESS ADDRESS:
    		STREET 1:		117 KENDRICK STREET
    		STREET 2:		SUITE 450
    		CITY:			NEEDHAM
    		STATE:			MA
    		ZIP:			02494
    		BUSINESS PHONE:		617-916-5445

    	MAIL ADDRESS:
    		STREET 1:		117 KENDRICK STREET
    		STREET 2:		SUITE 450
    		CITY:			NEEDHAM
    		STATE:			MA
    		ZIP:			02494

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Candel Therapeutics, Inic.
    		DATE OF NAME CHANGE:	20210120
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B4
    <SEQUENCE>1
    <FILENAME>d120909d424b4.htm
    <DESCRIPTION>424B4
    <TEXT>
    Document 1 - file: d120909d424b4.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>g120909g01e15.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: g120909g01e15.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>g120909g02y59.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: g120909g02y59.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>g120909g03t25.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: g120909g03t25.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>g120909g04w14.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: g120909g04w14.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>g120909g05n11.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 6 - file: g120909g05n11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>g120909g09b98.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 7 - file: g120909g09b98.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>g120909g11i11.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: g120909g11i11.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>g120909g15d66.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: g120909g15d66.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>g120909g17h55.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: g120909g17h55.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>g120909g22i22.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: g120909g22i22.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>g120909g29h20.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: g120909g29h20.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>g120909g29w29.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: g120909g29w29.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>g120909g33i33.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: g120909g33i33.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>g120909g35d25.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 15 - file: g120909g35d25.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>g120909g37m21.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 16 - file: g120909g37m21.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>g120909g42e26.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 17 - file: g120909g42e26.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>g120909g44a52.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 18 - file: g120909g44a52.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>g120909g44i66.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 19 - file: g120909g44i66.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>g120909g45h32.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 20 - file: g120909g45h32.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>g120909g46g30.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 21 - file: g120909g46g30.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>g120909g46q45.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 22 - file: g120909g46q45.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>g120909g66n88.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 23 - file: g120909g66n88.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>g120909g77p33.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 24 - file: g120909g77p33.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>g120909g90h66.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 25 - file: g120909g90h66.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>g120909g96s82.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 26 - file: g120909g96s82.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>27
    <FILENAME>g120909g98k04.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 27 - file: g120909g98k04.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>28
    <FILENAME>g120909g99c98.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 28 - file: g120909g99c98.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>29
    <FILENAME>g120909g99i99.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 29 - file: g120909g99i99.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>