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Insider Trading Arrangements | 3 Months Ended
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Mar. 31, 2026 shares
Trading Arrangements, by Individual |
Material Terms of Trading Arrangement | The following table describes contracts, instructions or written plans for the sale or purchase of our securities adopted by our directors and certain officers during the three months ended March 31, 2026, each of which is intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c), referred to as Rule 10b5-1 trading plans.
Name | Action Taken | Nature of Trading Arrangement | Duration of Trading Arrangement | Aggregate Number of Securities
Paul Peter Tak, M.D., Ph.D., FMedSci (Chief Executive Officer, President and Director) | Adoption (March 13, 2026) | Trading plan intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c) | Earlier of (i) June 30, 2027 and (ii) the completed sale of the maximum aggregate number of securities under the plan | Up to 880,245 shares
Charles Schoch (Chief Financial Officer, Treasurer and Secretary) | Adoption (March 13, 2026) | Trading plan intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c) | Earlier of (i) June 30, 2028 and (ii) the completed sale of the maximum aggregate number of securities under the plan | Up to 38,038 shares
Francesca Barone, M.D., Ph.D. (Chief Scientific Officer) | Adoption (March 16, 2026) | Trading plan intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c) | Earlier of (i) June 30, 2028 and (ii) the completed sale of the maximum aggregate number of securities under the plan | Up to 93,789 shares
W. Garrett Nichols, M.D., M.S. (Chief Medical Officer) | Adoption (March 16, 2026) | Trading plan intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c) | Earlier of (i) November 1, 2027 and (ii) the completed sale of the maximum aggregate number of securities under the plan | Up to 52,493 shares
Seshu Tyagarajan, Ph.D., RAC (Chief Technical and Development Director) | Adoption (March 16, 2026) | Trading plan intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c) | Earlier of (i) March 31, 2028 and (ii) the completed sale of the maximum aggregate number of securities under the plan | Up to 128,564 shares
No other directors or officers (as defined in Rule 16a-1(f) under the Exchange Act) adopted, modified and/or terminated a “Rule 10b5-1 trading arrangement” or a “non-Rule 10b5-1 trading arrangement,” as defined in Regulation S-K Item 408, during the three months ended March 31, 2026.
Rule 10b5-1 Arrangement Adopted | false
Non-Rule 10b5-1 Arrangement Adopted | false
Rule 10b5-1 Arrangement Terminated | false
Non-Rule 10b5-1 Arrangement Terminated | false
Rule 10b51 Arr Modified Flag | false
Non Rule 10b51 Arr Modified Flag | false
Paul Peter Tak |
Trading Arrangements, by Individual |
Name | Paul Peter Tak
Title | Chief Executive Officer, President and Director
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | March 13, 2026
Expiration Date | June 30, 2027
Aggregate Available | 880,245
Charles Schoch |
Trading Arrangements, by Individual |
Name | Charles Schoch
Title | Chief Financial Officer, Treasurer and Secretary
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | March 13, 2026
Expiration Date | June 30, 2028
Aggregate Available | 38,038
Francesca Barone |
Trading Arrangements, by Individual |
Name | Francesca Barone
Title | Chief Scientific Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | March 16, 2026
Expiration Date | June 30, 2028
Aggregate Available | 93,789
W. Garrett Nichols |
Trading Arrangements, by Individual |
Name | W. Garrett Nichols
Title | Chief Medical Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | March 16, 2026
Expiration Date | November 1, 2027
Aggregate Available | 52,493
Seshu Tyagarajan |
Trading Arrangements, by Individual |
Name | Seshu Tyagarajan
Title | Chief Technical and Development Director
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | March 16, 2026
Expiration Date | March 31, 2028
Aggregate Available | 128,564

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