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Stock-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2012
Stock-Based Compensation [Abstract]  
Activity under the Company's equity incentive plans related to stock options

Activity under the Company’s equity incentive plans related to stock options is set forth below (in thousands except per share amounts):

 

                 
    Number of Options
Outstanding
    Weighted
Average
Exercise
Price per
Share
 

Balance at December 31, 2011

    7,362     $ 4.70  

Granted

    1,750       3.69  

Forfeited

    (29     2.43  

Expired

    (276     36.91  

Exercised

    (106     1.46  
   

 

 

         

Balance at June 30, 2012

    8,701     $ 3.52  
   

 

 

         
Recognition of stock-based compensation expense

Stock-based compensation recognized on the Company’s condensed consolidated statements of operations for the three and six months ended June 30, 2012, and 2011, was as follows (in thousands):

 

                                 
    Three Months Ended
June 30,
    Six Months Ended
June 30,
 
    2012     2011     2012     2011  

Stock-based compensation expense by caption:

                               

Research and development

  $ 146     $ 111     $ 277     $ 220  

Selling, general and administrative

    528       340       939       703  
   

 

 

   

 

 

   

 

 

   

 

 

 

Total stock-based compensation expense

  $ 674     $ 451     $ 1,216     $ 923