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Stockholders' Equity (Details Textual) (USD $) | 3 Months Ended | 9 Months Ended |  | 6 Months Ended | 9 Months Ended |  | 3 Months Ended | 9 Months Ended | 12 Months Ended | 3 Months Ended | 9 Months Ended | 6 Months Ended | 1 Months Ended |  |
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Sep. 30, 2012 | Sep. 30, 2011 | Sep. 30, 2012 | Sep. 30, 2011 | Dec. 31, 2011 | Jun. 30, 2012 Series B preferred stock [Member] | Sep. 30, 2012 Series B preferred stock [Member] | Mar. 31, 1999 Series B preferred stock [Member] | Sep. 30, 2012 Sales Agreement [Member] MLV [Member] | Sep. 30, 2012 Sales Agreement [Member] MLV [Member] | Dec. 31, 2011 Sales Agreement [Member] MLV [Member] | Sep. 30, 2012 Sales Agreement [Member] Cantor [Member] | Sep. 30, 2012 Sales Agreement [Member] Cantor [Member] | Sep. 30, 2012 Stockholder Rights Plan [Member] | Jun. 30, 2012 Common stock [Member] | Aug. 31, 2009 Warrant [Member] 2009 Unit Offering [Member] | Nov. 30, 2010 Warrant [Member] 2010 Unit Offering [Member] | Jun. 30, 2012 Warrant [Member] 2010 Unit Offering [Member] | Dec. 31, 2011 Warrant [Member] 2010 Unit Offering [Member]
Stockholders' Equity (Textual) [Abstract] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Preferred stock issued |  |  |  |  |  |  |  | 3,327 |  |  |  |  |  |  |  |  |  |  |
Preferred stock conversion basis to common shares |  |  |  |  |  |  | 100 |  |  |  |  |  |  |  |  |  |  |  |
Common stock issued to Fenwal |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 332,700 |  |  |  |
Conversion of preferred stock to Common stock |  |  |  |  |  | 3,327 |  |  |  |  |  |  |  |  |  |  |  |  |
Conversion of preferred stock to common stock date |  |  |  |  |  |  |  |  |  |  |  |  |  |  | Jun. 30, 2012 |  |  |  |
Redeemable preferred stock, amount |  |  |  |  |  | $ 9,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants to purchase an aggregate shares of common stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2,400,000 | 3,700,000 |  |
Warrants exercise price |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2.90 | 3.20 |  |
Exercisable period |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5 years | 5 years |  |
Warrant liability | 7,876,000 |  | 7,876,000 |  | 7,979,000 |  |  |  |  |  |  |  |  |  |  | 2,800,000 | 5,800,000 |  |
Risk-free rate |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2.48% | 1.23% |  |
Expected term |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5 years | 5 years |  |
Dividend yield |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 0.00% | 0.00% |  |
Volatility |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 77.00% | 85.00% |  |
Warrants exercised |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,084 | 0
Maximum common stock offering price |  |  |  |  |  |  |  |  |  | 20,000,000 |  |  | 30,000,000 |  |  |  |  |  |
Percentage of proceeds payable as compensation to underwriter |  |  |  |  |  |  |  |  |  | 3.00% |  |  | 2.00% |  |  |  |  |  |
Common stock, sold |  |  |  |  |  |  |  |  | 0 | 3,100,000 | 3,500,000 | 400,000 | 400,000 |  |  |  |  |  |
Minimum percentage of common stock acquired by stockholders |  |  |  |  |  |  |  |  |  |  |  |  |  | 15.00% |  |  |  |  |
Designated preferred stock for future issuance |  |  |  |  |  |  |  |  |  |  |  |  |  | 250,000 |  |  |  |  |
Proceeds from common stock sold |  |  | 10,823,000 | 0 |  |  |  |  | 0 | 9,500,000 | 9,700,000 | 1,100,000 | 1,100,000 |  |  |  |  |  |
Stockholders' Equity (Additional Textual) [Abstract] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revaluation of warrant liability | $ 873,000 | $ 5,439,000 | $ 86,000 | $ 3,822,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

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