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Stockholders' Equity (Details Textual) (USD $)
 3 Months Ended 9 Months Ended 6 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 3 Months Ended 9 Months Ended 6 Months Ended 1 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Jun. 30, 2012
Series B preferred stock [Member]
Sep. 30, 2012
Series B preferred stock [Member]
Mar. 31, 1999
Series B preferred stock [Member]
Sep. 30, 2012
Sales Agreement [Member]
MLV [Member]
Sep. 30, 2012
Sales Agreement [Member]
MLV [Member]
Dec. 31, 2011
Sales Agreement [Member]
MLV [Member]
Sep. 30, 2012
Sales Agreement [Member]
Cantor [Member]
Sep. 30, 2012
Sales Agreement [Member]
Cantor [Member]
Sep. 30, 2012
Stockholder Rights Plan [Member]
Jun. 30, 2012
Common stock [Member]
Aug. 31, 2009
Warrant [Member]
2009 Unit Offering [Member]
Nov. 30, 2010
Warrant [Member]
2010 Unit Offering [Member]
Jun. 30, 2012
Warrant [Member]
2010 Unit Offering [Member]
Dec. 31, 2011
Warrant [Member]
2010 Unit Offering [Member]
Stockholders' Equity (Textual) [Abstract]                                      
Preferred stock issued               3,327                      
Preferred stock conversion basis to common shares             100                        
Common stock issued to Fenwal                             332,700        
Conversion of preferred stock to Common stock           3,327                          
Conversion of preferred stock to common stock date                             Jun. 30, 2012        
Redeemable preferred stock, amount           $ 9,500,000                          
Warrants to purchase an aggregate shares of common stock                               2,400,000 3,700,000    
Warrants exercise price                               2.90 3.20    
Exercisable period                               5 years 5 years    
Warrant liability 7,876,000   7,876,000   7,979,000                     2,800,000 5,800,000    
Risk-free rate                               2.48% 1.23%    
Expected term                               5 years 5 years    
Dividend yield                               0.00% 0.00%    
Volatility                               77.00% 85.00%    
Warrants exercised                                   5,084 0
Maximum common stock offering price                   20,000,000     30,000,000            
Percentage of proceeds payable as compensation to underwriter                   3.00%     2.00%            
Common stock, sold                 0 3,100,000 3,500,000 400,000 400,000            
Minimum percentage of common stock acquired by stockholders                           15.00%          
Designated preferred stock for future issuance                           250,000          
Proceeds from common stock sold     10,823,000 0         0 9,500,000 9,700,000 1,100,000 1,100,000            
Stockholders' Equity (Additional Textual) [Abstract]                                      
Revaluation of warrant liability $ 873,000 $ 5,439,000 $ 86,000 $ 3,822,000