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Stockholders Equity - Additional Information (Detail) (USD $)
3 Months Ended 3 Months Ended 3 Months Ended 6 Months Ended 6 Months Ended 1 Months Ended 6 Months Ended 3 Months Ended 12 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Dec. 31, 2012
Mar. 31, 2013
IPO
Mar. 19, 2013
IPO
Mar. 31, 2013
IPO
Overallotment Option
Mar. 31, 2013
Stockholder Rights Plan
Mar. 31, 2013
Series B Convertible Preferred Stock
Jun. 30, 2012
Series B Convertible Preferred Stock
Mar. 31, 1999
Series B Convertible Preferred Stock
Jun. 30, 2012
Common Stock
Aug. 31, 2009
Warrant
2009 Unit Offering
Nov. 30, 2010
Warrant
2010 Unit Offering
Jun. 30, 2012
Warrant
2010 Unit Offering
Mar. 31, 2013
Sales Agreement
Mlv
Dec. 31, 2012
Sales Agreement
Mlv
Mar. 31, 2013
Sales Agreement
Mlv
Maximum
Mar. 31, 2013
Sales Agreement
Cantor
Dec. 31, 2012
Sales Agreement
Cantor
Stockholders Equity Note [Line Items]                                      
Preferred stock issued                   3,327                  
Preferred stock conversion basis to common shares               100                      
Redeemable preferred stock, amount                 $ 9,500,000                    
Conversion of preferred stock to Common stock                 3,327                    
Common stock issued to Fresenius                     332,700                
Conversion of preferred stock to common stock date                     Jun. 30, 2012                
Warrants to purchase an aggregate shares of common stock                       2,400,000 3,700,000            
Warrant exercise price                       2.90 3.20            
Exercisable period                       5 years 5 years            
Warrant liability 10,976,000   5,903,000                 2,800,000 5,800,000            
Risk-free rate                       2.48% 1.23%            
Expected term                       5 years 5 years            
Dividend yield                       0.00% 0.00%            
Volatility                       77.00% 85.00%            
Net proceeds from underwritten public offering                         19,700,000            
Payment for underwriting discounts and commissions and stock issuance cost       500,000                 1,300,000            
Number of units sold in underwritten public offering                         7,400,000            
Number of common stock in each unit                         1            
Number of common stock shares purchasable with each warrant                         0.5            
Units issued, price per unit                         $ 2.85            
Common stock, number of shares issued                         7,400,000   6,600,000     3,800,000 1,400,000
Warrants, number of common stock shares                         3,700,000            
Warrants exercisable date                         May 15, 2011            
Gain (Loss) from Revaluation of warrant liability (5,073,000) (4,461,000)                                  
Warrants exercised                           5,084          
Maximum common stock offering price                               20,000,000     30,000,000
Percentage of proceeds payable as compensation to underwriter                               3.00%     2.00%
Proceeds from common stock sold 51,502,000 9,612,000   38,000,000                     19,200,000     13,000,000 4,300,000
Common stock available for sale                                 100,000 12,500,000  
Common stock, number of shares issued       8,300,000   1,300,000                          
Common stock, price per share         $ 4.20                            
Gross proceeds from public offering       40,300,000                              
Underwriter's discount       $ 1,800,000                              
Minimum percentage of common stock acquired by stockholders             15.00%                        
Designated preferred stock for future issuance             250,000