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Quarterly Financial Information (Unaudited) (Tables) | 12 Months Ended
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Dec. 31, 2013
Quarterly Unaudited Financial Data | The following tables summarize the Company’s quarterly financial information for the years ended December 31, 2013 and 2012 (in thousands except per share amounts):
|  | Three Months Ended |
|  | March 31, 2013 |  |  | June 30, 2013 |  |  | September 30, 2013 |  |  | December 31, 2013 |
Revenue: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Product revenue |  | $ | 9,733 |  |  | $ | 10,150 |  |  | $ | 10,542 |  |  | $ | 9,232 |
Cost of product revenue |  |  | 5,090 |  |  |  | 5,747 |  |  |  | 6,826 |  |  |  | 4,939 |
Gross profit on product revenue |  |  | 4,643 |  |  |  | 4,403 |  |  |  | 3,716 |  |  |  | 4,293 |
Government grants and cooperative agreements revenue |  |  | — |  |  |  | — |  |  |  | — |  |  |  | — |
Operating expenses: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  | 2,700 |  |  |  | 3,506 |  |  |  | 4,363 |  |  |  | 4,618 |
Selling, general and administrative |  |  | 6,853 |  |  |  | 7,954 |  |  |  | 7,728 |  |  |  | 7,430 |
Amortization of intangible assets |  |  | 50 |  |  |  | 51 |  |  |  | 50 |  |  |  | 51 |
Total operating expenses |  |  | 9,603 |  |  |  | 11,511 |  |  |  | 12,141 |  |  |  | 12,099 |
Loss from operations |  |  | (4,960 | ) |  |  | (7,108 | ) |  |  | (8,425 | ) |  |  | (7,806 | )
Total non-operating income (expense), net |  |  | (5,241 | ) |  |  | 438 |  |  |  | (12,016 | ) |  |  | 1,999 |
Loss before income taxes |  |  | (10,201 | ) |  |  | (6,670 | ) |  |  | (20,441 | ) |  |  | (5,807 | )
Provision for income taxes |  |  | 51 |  |  |  | 54 |  |  |  | 60 |  |  |  | 53 |
Net loss |  | $ | (10,252 | ) |  | $ | (6,724 | ) |  | $ | (20,501 | ) |  | $ | (5,860 | )
Net loss per common share: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Basic |  | $ | (0.17 | ) |  | $ | (0.10 | ) |  | $ | (0.29 | ) |  | $ | (0.08 | )
Diluted |  | $ | (0.17 | ) |  | $ | (0.10 | ) |  | $ | (0.29 | ) |  | $ | (0.10 | )
|  | Three Months Ended |
|  | March 31, 2012 |  |  | June 30, 2012 |  |  | September 30, 2012 |  |  | December 31, 2012 |
Revenue: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Product revenue |  | $ | 8,691 |  |  | $ | 9,224 |  |  | $ | 8,252 |  |  | $ | 10,528 |
Cost of product revenue |  |  | 5,514 |  |  |  | 5,574 |  |  |  | 4,411 |  |  |  | 5,117 |
Gross profit on product revenue |  |  | 3,177 |  |  |  | 3,650 |  |  |  | 3,841 |  |  |  | 5,411 |
Government grants and cooperative agreements revenue |  |  | 91 |  |  |  | — |  |  |  | — |  |  |  | — |
Operating expenses: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Research and development |  |  | 1,824 |  |  |  | 1,712 |  |  |  | 1,903 |  |  |  | 2,164 |
Selling, general and administrative |  |  | 5,966 |  |  |  | 6,686 |  |  |  | 6,219 |  |  |  | 6,794 |
Amortization of intangible assets |  |  | 50 |  |  |  | 51 |  |  |  | 50 |  |  |  | 51 |
Total operating expenses |  |  | 7,840 |  |  |  | 8,449 |  |  |  | 8,172 |  |  |  | 9,009 |
Loss from operations |  |  | (4,572 | ) |  |  | (4,799 | ) |  |  | (4,331 | ) |  |  | (3,598 | )
Total non-operating income (expense), net |  |  | (4,227 | ) |  |  | 2,933 |  |  |  | 926 |  |  |  | 1,993 |
Loss before income taxes |  |  | (8,799 | ) |  |  | (1,866 | ) |  |  | (3,405 | ) |  |  | (1,605 | )
Provision for income taxes |  |  | 35 |  |  |  | 41 |  |  |  | 55 |  |  |  | 111 |
Net loss |  | $ | (8,834 | ) |  | $ | (1,907 | ) |  | $ | (3,460 | ) |  | $ | (1,716 | )
Net loss per common share: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Basic |  | $ | (0.17 | ) |  | $ | (0.04 | ) |  | $ | (0.06 | ) |  | $ | (0.03 | )
Diluted |  | $ | (0.17 | ) |  | $ | (0.10 | ) |  | $ | (0.08 | ) |  | $ | (0.07 | )

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- Definition Tabular disclosure of the quarterly financial data in the annual financial statements. The disclosure includes financial information for each fiscal quarter for the current and previous year, including revenues, gross profit, income (loss) before extraordinary items and cumulative effect of a change in accounting principle and earnings per share data. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=25249566&loc=d3e1280-108306 + Details
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