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CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Per Share data, unless otherwise specified
 12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Product related:      
Product revenue $ 39,657 $ 36,695 $ 30,602
Cost of product revenue 22,602 20,616 18,535
Gross profit on product revenue 17,055 16,079 12,067
Government grants and cooperative agreements revenue 0 91 2,442
Operating expenses:      
Research and development 15,187 7,603 7,178
Selling, general and administrative 29,965 25,665 23,053
Amortization of intangible assets 202 202 202
Total operating expenses 45,354 33,470 30,433
Loss from operations (28,299) (17,300) (15,924)
Non-operating (expense) income, net:      
Revaluation of warrant liability (15,099) 2,059 486
Foreign exchange gain (loss) 533 86 (529)
Interest expense (520) (551) (964)
Other income, net 266 31 92
Total non-operating (expense) income, net (14,820) 1,625 (915)
Loss before income taxes (43,119) (15,675) (16,839)
Provision for income taxes 218 242 143
Net loss $ (43,337) $ (15,917) $ (16,982)
Net loss per common share:      
Basic $ (0.64) $ (0.29) $ (0.35)
Diluted $ (0.64) $ (0.33) $ (0.35)
Weighted average common shares outstanding used for calculating net loss per common share:      
Basic 67,569 54,515 48,050
Diluted 67,569 55,061 48,050