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Development and License Agreements - Additional Information (Detail) (USD $)
 1 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2013
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Licenses Agreements [Line Items]          
Royalty payments on products     $ 3,000,000 $ 2,700,000 $ 2,200,000
Payments made relating to the manufacturing of the products     15,000,000 12,200,000 9,600,000
Prior written notice for termination of agreement 24 months        
Current asset, warrant claim 442,000   442,000 2,038,000  
Revenue from cooperative agreement   91,000 0 91,000 2,442,000
Product Warranty
          
Licenses Agreements [Line Items]          
Current asset, warrant claim       1,800,000  
Fresenius
          
Licenses Agreements [Line Items]          
Prior written notice for termination of agreement 30 months        
Royalty
          
Licenses Agreements [Line Items]          
Manufacturing costs owed 700,000   700,000 800,000  
Royalty | Platelet system
          
Licenses Agreements [Line Items]          
Royalty rate applied towards sale of products     10.00%    
Royalty | Plasma system
          
Licenses Agreements [Line Items]          
Royalty rate applied towards sale of products     3.00%    
Manufacturing Costs
          
Licenses Agreements [Line Items]          
Manufacturing costs owed $ 4,300,000   $ 4,300,000 $ 6,200,000