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Summary of Quarterly Financial Information (Detail) (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 12 Months Ended
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Quarterly Financial Information [Line Items]                      
Product revenue $ 9,232 $ 10,542 $ 10,150 $ 9,733 $ 10,528 $ 8,252 $ 9,224 $ 8,691 $ 39,657 $ 36,695 $ 30,602
Cost of product revenue 4,939 6,826 5,747 5,090 5,117 4,411 5,574 5,514 22,602 20,616 18,535
Gross profit on product revenue 4,293 3,716 4,403 4,643 5,411 3,841 3,650 3,177 17,055 16,079 12,067
Government grants and cooperative agreements revenue               91 0 91 2,442
Research and development 4,618 4,363 3,506 2,700 2,164 1,903 1,712 1,824 15,187 7,603 7,178
Selling, general and administrative 7,430 7,728 7,954 6,853 6,794 6,219 6,686 5,966 29,965 25,665 23,053
Amortization of intangible assets 51 50 51 50 51 50 51 50 202 202 202
Total operating expenses 12,099 12,141 11,511 9,603 9,009 8,172 8,449 7,840 45,354 33,470 30,433
Loss from operations (7,806) (8,425) (7,108) (4,960) (3,598) (4,331) (4,799) (4,572) (28,299) (17,300) (15,924)
Total non-operating income (expense), net 1,999 (12,016) 438 (5,241) 1,993 926 2,933 (4,227) (14,820) 1,625 (915)
Loss before income taxes (5,807) (20,441) (6,670) (10,201) (1,605) (3,405) (1,866) (8,799) (43,119) (15,675) (16,839)
Provision for income taxes 53 60 54 51 111 55 41 35 218 242 143
Net loss $ (5,860) $ (20,501) $ (6,724) $ (10,252) $ (1,716) $ (3,460) $ (1,907) $ (8,834) $ (43,337) $ (15,917) $ (16,982)
Basic $ (0.08) $ (0.29) $ (0.10) $ (0.17) $ (0.03) $ (0.06) $ (0.04) $ (0.17) $ (0.64) $ (0.29) $ (0.35)
Diluted $ (0.10) $ (0.29) $ (0.10) $ (0.17) $ (0.07) $ (0.08) $ (0.10) $ (0.17) $ (0.64) $ (0.33) $ (0.35)