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Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2016 | Dec. 31, 2015 | Dec. 31, 2014
Income Tax Disclosure [Line Items] |  |  |
Increase in valuation allowance | $ 13,600 | $ 11,800 | $ 14,100
Loss before income taxes | (62,731) | (59,539) | $ (38,560)
Operating loss carryforwards related to windfall tax deductions | 2,800 |  |
Research and development tax credit carryforwards | 31,777 | $ 35,131 |
Internal Revenue Service (IRS) |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards | 503,000 |  |
Research and development tax credit carryforwards | $ 23,900 |  |
Internal Revenue Service (IRS) | Minimum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2017 |  |
Research and development tax credit carryforwards, expiration year | 2018 |  |
Internal Revenue Service (IRS) | Maximum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2036 |  |
Research and development tax credit carryforwards, expiration year | 2036 |  |
California Franchise Tax Board | Latest Tax Year |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax year remain subject to examination by the taxing jurisdictions | 1998 |  |
California Franchise Tax Board | Latest Tax Year |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax year remain subject to examination by the taxing jurisdictions | 2015 |  |
Tax and Customs Administration, Netherlands | Latest Tax Year |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax year remain subject to examination by the taxing jurisdictions | 2013 |  |
Tax and Customs Administration, Netherlands | Latest Tax Year |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax year remain subject to examination by the taxing jurisdictions | 2015 |  |
State and Local Jurisdiction |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards | $ 94,000 |  |
Research and development tax credit carryforwards | $ 11,900 |  |
State and Local Jurisdiction | Minimum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2017 |  |
State and Local Jurisdiction | Maximum |  |  |
Income Tax Disclosure [Line Items] |  |  |
Net operating loss carryforwards, expiration year | 2036 |  |
Domestic Tax Authority | Latest Tax Year |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax year remain subject to examination by the taxing jurisdictions | 1998 |  |
Domestic Tax Authority | Latest Tax Year |  |  |
Income Tax Disclosure [Line Items] |  |  |
Tax year remain subject to examination by the taxing jurisdictions | 2015 |  |
Cerus Europe B.V. |  |  |
Income Tax Disclosure [Line Items] |  |  |
Undistributed earning of foreign subsidiary | $ 5,200 |  |
Unrecognized deferred tax liability for unrepatriated earnings | $ 1,900 |  |

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