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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2016
Income Tax Disclosure [Abstract] |
United States and Foreign Components of Consolidated Loss Before Income Taxes | U.S and foreign components of consolidated loss before income taxes for the years ended December 31, 2016, 2015 and 2014, was as follows (in thousands):
|  | 2016 |  |  | 2015 |  |  | 2014 |
Loss before income taxes: |  |  |  |  |  |  |  |  |  |  |  |
U.S. |  | $ | (63,246 | ) |  | $ | (59,897 | ) |  | $ | (38,928 | )
Foreign |  |  | 515 |  |  |  | 358 |  |  |  | 368 |
Loss before income taxes |  | $ | (62,731 | ) |  | $ | (59,539 | ) |  | $ | (38,560 | )
Provision Benefit for Income Taxes | The provision for income taxes for the years ended December 31, 2016, 2015 and 2014, was as follows (in thousands):
|  | 2016 |  |  | 2015 |  |  | 2014 |
Provision for income taxes: |  |  |  |  |  |  |  |  |  |  |  |
Current: |  |  |  |  |  |  |  |  |  |  |  |
Foreign |  | $ | 147 |  |  | $ | 147 |  |  | $ | 168 |
Federal |  |  | — |  |  |  | — |  |  |  | — |
State |  |  | — |  |  |  | — |  |  |  | 1 |
Total current |  |  | 147 |  |  |  | 147 |  |  |  | 169 |
Deferred: |  |  |  |  |  |  |  |  |  |  |  |
Foreign |  |  | — |  |  |  | — |  |  |  | — |
Federal |  |  | 28 |  |  |  | (3,750 | ) |  |  | 22 |
State |  |  | — |  |  |  | (68 | ) |  |  | 4 |
Total deferred |  |  | 28 |  |  |  | (3,818 | ) |  |  | 26 |
Provision (benefit) for income taxes |  | $ | 175 |  |  | $ | (3,671 | ) |  | $ | 195 |
Difference Between Provision for Income Taxes and Amounts Computed by Applying Federal Statutory Income Tax Rate to Loss before Taxes | The difference between the provision for income taxes and the amount computed by applying the federal statutory income tax rate to loss before taxes for the years ended December 31, 2016, 2015 and 2014, was as follows (in thousands):
|  | 2016 |  |  | 2015 |  |  | 2014 |
Federal statutory tax |  | $ | (21,329 | ) |  | $ | (20,243 | ) |  | $ | (13,110 | )
Warrants |  |  | — |  |  |  | (3,565 | ) |  |  | (3,367 | )
Expiration of federal loss carryovers |  |  | — |  |  |  | 3,337 |  |  |  | — |
Change in valuation allowance |  |  | 13,589 |  |  |  | 11,754 |  |  |  | 16,576 |
Change in state apportionment |  |  | — |  |  |  | 4,085 |  |  |  | — |
Revision to prior year items |  |  | 7,551 |  |  |  | — |  |  |  | — |
Other |  |  | 364 |  |  |  | 961 |  |  |  | 96 |
Provision (benefit) for income taxes |  | $ | 175 |  |  | $ | (3,671 | ) |  | $ | 195 |
Significant Components of Deferred Tax Assets and Liabilities | The significant components of the Company’s deferred tax assets and liabilities at December 31, 2016 and 2015, were as follows (in thousands):
|  | December 31, |
|  | 2016 |  |  | 2015 |
Deferred tax assets: |  |  |  |  |  |  |  |
Net operating loss carryforwards |  | $ | 176,490 |  |  | $ | 165,813 |
Research and development credit carryforwards |  |  | 31,777 |  |  |  | 35,131 |
Capitalized research and development |  |  | 22,575 |  |  |  | 17,916 |
Deferred compensation |  |  | 8,242 |  |  |  | 5,908 |
Other |  |  | 3,184 |  |  |  | 3,911 |
Total deferred tax assets |  |  | 242,268 |  |  |  | 228,679 |
Valuation allowance |  |  | (238,443 | ) |  |  | (224,854 | )
Net deferred tax assets |  | $ | 3,825 |  |  | $ | 3,825 |
Deferred tax liabilities: |  |  |  |  |  |  |  |
Unrealized gain on investments |  | $ | 3,825 |  |  | $ | 3,825 |
Amortization of goodwill |  |  | 150 |  |  |  | 122 |
Total deferred tax liabilities |  | $ | 3,975 |  |  | $ | 3,947 |
Reconciliation of Unrecognized Tax Benefits | The following is a tabular reconciliation of the total amounts of unrecognized tax benefits (in thousands):
|  | December 31, |
|  | 2016 |
Unrecognized tax benefits at beginning of period |  | $ | — |
Increases related to prior year tax positions |  |  | 10,691 |
Increases related to current year tax positions |  |  | 145 |
Unrecognized tax benefits at beginning of period |  | $ | 10,836 |

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=65882285&loc=d3e32639-109319 + Details
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