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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Income Statement [Abstract]        
Product revenue $ 9,525 $ 9,251 $ 16,531 $ 16,883
Cost of product revenue 4,360 4,976 8,054 9,239
Gross profit on product revenue 5,165 4,275 8,477 7,644
Government contracts revenue 1,667   3,095  
Operating expenses:        
Research and development 8,891 8,557 18,041 15,474
Selling, general and administrative 14,094 12,406 27,727 24,153
Amortization of intangible assets 51 51 101 101
Total operating expenses 23,036 21,014 45,869 39,728
Loss from operations (16,204) (16,739) (34,297) (32,084)
Non-operating income (expense), net:        
Foreign exchange (loss) gain (14) 101 (59) (16)
Interest expense (501) (658) (1,032) (1,313)
Other income, net 3,512 113 3,618 179
Total non-operating income (expense), net 2,997 (444) 2,527 (1,150)
Loss before income taxes (13,207) (17,183) (31,770) (33,234)
Provision for income taxes 3,876 983 3,911 1,795
Net loss $ (17,083) $ (18,166) $ (35,681) $ (35,029)
Net loss per share:        
Basic $ (0.16) $ (0.18) $ (0.34) $ (0.35)
Diluted $ (0.16) $ (0.18) $ (0.34) $ (0.35)
Weighted average shares outstanding used for calculating net loss per share:        
Basic 105,044 101,563 104,308 100,517
Diluted 105,044 101,563 104,308 100,517