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Summary of Quarterly Financial Information (Detail) - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2017 | Sep. 30, 2017 | Jun. 30, 2017 | Mar. 31, 2017 | Dec. 31, 2016 | Sep. 30, 2016 | Jun. 30, 2016 | Mar. 31, 2016 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract] |  |  |  |  |  |  |  |  |  |  |
Product revenue | $ 16,240 | $ 10,797 | $ 9,525 | $ 7,006 | $ 10,125 | $ 10,175 | $ 9,251 | $ 7,632 | $ 43,568 | $ 37,183 | $ 34,223
Gross profit on product revenue | 7,111 | 5,449 | 5,165 | 3,312 | 4,520 | 4,724 | 4,275 | 3,369 | 21,037 | 16,888 | 10,759
Government contract revenue | 2,378 | 2,285 | 1,667 | 1,428 | 1,831 | 261 |  |  | 7,758 | 2,092 |
Net loss | $ (11,486) | $ (13,418) | $ (17,083) | $ (18,598) | $ (13,501) | $ (14,376) | $ (18,166) | $ (16,863) | $ (60,585) | $ (62,906) | $ (55,868)
Basic | $ (0.10) | $ (0.12) | $ (0.16) | $ (0.18) | $ (0.13) | $ (0.14) | $ (0.18) | $ (0.17) | $ (0.56) | $ (0.62) | $ (0.58)
Diluted | $ (0.10) | $ (0.12) | $ (0.16) | $ (0.18) | $ (0.13) | $ (0.14) | $ (0.18) | $ (0.17) | $ (0.56) | $ (0.62) | $ (0.61)

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