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Gross Amounts and Dates of Expiration of Tax Credits and Carryovers (Detail) - USD ($) $ in Thousands | Dec. 31, 2017 | Dec. 31, 2016
--- | --- | ---
Income Tax Disclosure [Line Items] |  |
Federal losses carryovers | $ 531,303 |
California loss carryovers | 73,860 |
Research credits | 25,061 | $ 22,128
Federal foreign tax credits | 610 |
Federal |  |
Income Tax Disclosure [Line Items] |  |
Research credits | 17,642 |
California |  |
Income Tax Disclosure [Line Items] |  |
Research credits | 9,391 |
Expires 2018-2020 |  |
Income Tax Disclosure [Line Items] |  |
Federal losses carryovers | 74,073 |
California loss carryovers | 19,243 |
Expires 2018-2020 | Federal |  |
Income Tax Disclosure [Line Items] |  |
Research credits | 3,262 |
Expires 2021-2027 |  |
Income Tax Disclosure [Line Items] |  |
Federal losses carryovers | 145,248 |
Federal foreign tax credits | 610 |
Expires 2021-2027 | Federal |  |
Income Tax Disclosure [Line Items] |  |
Research credits | 9,866 |
Expires 2028-2037 |  |
Income Tax Disclosure [Line Items] |  |
Federal losses carryovers | 311,982 |
California loss carryovers | 54,617 |
Expires 2028-2037 | Federal |  |
Income Tax Disclosure [Line Items] |  |
Research credits | 4,514 |
No Expiration | California |  |
Income Tax Disclosure [Line Items] |  |
Research credits | $ 9,391 |

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