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Marketable Equity Investments - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
Apr. 30, 2015
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Investment [Line Items]        
Eligibility to receive a royalty fee   1.00%    
Royalty income, nonoperating   $ 0 $ 0 $ 0
Carrying value of investment   0    
Gain on sale of investment in marketable equity securities   $ 3,466,000 $ 750,000  
Remaining investment in common stock   103,475,000 103,475,000  
Aduro        
Investment [Line Items]        
Preferred shares converted to common stock 396,700      
Sale of common stock in marketable equity investment   346,700 50,000  
Gain on sale of investment in marketable equity securities   $ 3,500,000 $ 800,000  
Remaining investment in common stock   0