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Gross Amounts and Dates of Expiration of Tax Credits and Carryovers (Detail) - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Income Tax Disclosure [Line Items]
Federal losses carryovers	$ 531,303
California loss carryovers	73,860
Research credits	25,061	$ 22,128
Federal foreign tax credits	610
Federal
Income Tax Disclosure [Line Items]
Research credits	17,642
California
Income Tax Disclosure [Line Items]
Research credits	9,391
Expires 2018-2020
Income Tax Disclosure [Line Items]
Federal losses carryovers	74,073
California loss carryovers	19,243
Expires 2018-2020 | Federal
Income Tax Disclosure [Line Items]
Research credits	3,262
Expires 2021-2027
Income Tax Disclosure [Line Items]
Federal losses carryovers	145,248
Federal foreign tax credits	610
Expires 2021-2027 | Federal
Income Tax Disclosure [Line Items]
Research credits	9,866
Expires 2028-2037
Income Tax Disclosure [Line Items]
Federal losses carryovers	311,982
California loss carryovers	54,617
Expires 2028-2037 | Federal
Income Tax Disclosure [Line Items]
Research credits	4,514
No Expiration | California
Income Tax Disclosure [Line Items]
Research credits	$ 9,391

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