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Summary of Quarterly Financial Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Quarterly Financial Information Disclosure [Abstract]                      
Product revenue $ 16,240 $ 10,797 $ 9,525 $ 7,006 $ 10,125 $ 10,175 $ 9,251 $ 7,632 $ 43,568 $ 37,183 $ 34,223
Gross profit on product revenue 7,111 5,449 5,165 3,312 4,520 4,724 4,275 3,369 21,037 16,888 10,759
Government contract revenue 2,378 2,285 1,667 1,428 1,831 261     7,758 2,092  
Net loss $ (11,486) $ (13,418) $ (17,083) $ (18,598) $ (13,501) $ (14,376) $ (18,166) $ (16,863) $ (60,585) $ (62,906) $ (55,868)
Basic $ (0.10) $ (0.12) $ (0.16) $ (0.18) $ (0.13) $ (0.14) $ (0.18) $ (0.17) $ (0.56) $ (0.62) $ (0.58)
Diluted $ (0.10) $ (0.12) $ (0.16) $ (0.18) $ (0.13) $ (0.14) $ (0.18) $ (0.17) $ (0.56) $ (0.62) $ (0.61)