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Shares Underlying Stock Options, Excluded from Calculation of Weighted Average Number of Shares Outstanding used for Calculation of Diluted Net Loss Per Share (Detail) - shares
shares in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Weighted average number of anti-dilutive potential shares 19,550 17,635
Stock Options    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Weighted average number of anti-dilutive potential shares 17,879 16,669
Restricted Stock Units    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Weighted average number of anti-dilutive potential shares 1,579 966
Employee Stock Purchase Plan Rights    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Weighted average number of anti-dilutive potential shares 92