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CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($) shares in Thousands, $ in Thousands | Total | Common Stock | Additional Paid-in Capital | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit
--- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2017 | $ 38,940 | $ 115 | $ 760,225 | $ (97) | $ (721,303)
Balance (in shares) at Dec. 31, 2017 |  | 115,555 |  |  |
Net loss | (13,885) |  |  |  | (13,885)
Other comprehensive income (loss) | (329) |  |  | (329) |
Issuance of common stock from public offering, net of offering costs | 57,262 | $ 15 | 57,247 |  |
Issuance of common stock from public offering, net of offering costs (in shares) |  | 14,039 |  |  |
Issuance of common stock from exercise of stock options, vesting of restricted stock units, and ESPP purchases | 1,295 | $ 1 | 1,294 |  |
Issuance of common stock from exercise of stock options, vesting of restricted stock units, and ESPP purchases (in shares) |  | 951 |  |  |
Stock-based compensation | 2,315 |  | 2,315 |  |
Balance at Mar. 31, 2018 | 85,598 | $ 131 | 821,081 | (426) | (735,188)
Balance (in shares) at Mar. 31, 2018 |  | 130,545 |  |  |
Balance at Dec. 31, 2018 | 84,519 | $ 136 | 863,531 | (281) | (778,867)
Balance (in shares) at Dec. 31, 2018 |  | 136,853 |  |  |
Net loss | (18,792) |  |  |  | (18,792)
Other comprehensive income (loss) | 211 |  |  | 211 |
Issuance of common stock from exercise of stock options, vesting of restricted stock units, and ESPP purchases | 684 | $ 2 | 682 |  |
Issuance of common stock from exercise of stock options, vesting of restricted stock units, and ESPP purchases (in shares) |  | 965 |  |  |
Stock-based compensation | 2,878 |  | 2,878 |  |
Balance at Mar. 31, 2019 | $ 69,500 | $ 138 | $ 867,091 | $ (70) | $ (797,659)
Balance (in shares) at Mar. 31, 2019 |  | 137,818 |  |  |

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