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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2019 | Jun. 30, 2018
Operating activities |  |
Net loss | $ (36,354) | $ (27,167)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 1,908 | 788
Stock-based compensation | 6,017 | 4,908
Non-cash interest expense | 247 | 537
Loss on disposal of property and equipment | 14 | 5
Changes in operating assets and liabilities: |  |
Accounts receivable | (4,680) | 1,027
Inventories | (3,977) | 1,458
Other assets | 1,817 | (1,587)
Accounts payable | 3,229 | 154
Accrued liabilities and other non-current liabilities | (3,410) | 554
Manufacturing and development obligations | (38) | (148)
Deferred product revenue | 167 | 216
Net cash used in operating activities | (35,060) | (19,255)
Investing activities |  |
Capital expenditures | (6,516) | (145)
Purchases of investments | (27,728) | (75,462)
Proceeds from maturities and sale of investments | 43,000 | 24,002
Net cash provided by (used in) investing activities | 8,756 | (51,605)
Financing activities |  |
Net proceeds from equity incentives | 1,270 | 4,912
Net proceeds from public offering | 6,783 | 69,117
Net proceeds from revolving line of credit | 4,496 |
Proceeds from loans | 39,433 |
Repayment of debt | (31,045) | (65)
Net cash provided by financing activities | 20,937 | 73,964
Net (decrease) increase in cash, cash equivalents and restricted cash | (5,367) | 3,104
Cash, cash equivalents and restricted cash, beginning of period | 31,587 | 13,930
Cash, cash equivalents and restricted cash, end of period | $ 26,220 | $ 17,034

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