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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2020 | Mar. 31, 2019
Operating activities |  |
Net loss | $ (16,466) | $ (18,792)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 706 | 376
Stock-based compensation | 3,754 | 2,878
Non-cash operating lease cost | 300 | 353
Loss on sale of available-for-sale securities | 267 |
Non-cash interest expense | 119 | 197
Changes in operating assets and liabilities: |  |
Accounts receivable | (1,283) | (5,004)
Inventories | (2,226) | (2,286)
Other assets | 1,119 | 2,165
Accounts payable | (2,308) | 2,597
Accrued liabilities and other non-current liabilities | (4,356) | (4,809)
Manufacturing and development obligations |  | (118)
Deferred product revenue | 572 | 265
Net cash used in operating activities | (19,802) | (22,178)
Investing activities |  |
Capital expenditures | (452) | (3,315)
Purchases of investments | (68,520) | (1,000)
Proceeds from maturities and sale of investments | 18,787 | 17,500
Net cash (used in) provided by investing activities | (50,185) | 13,185
Financing activities |  |
Net proceeds from equity incentives | 1,193 | 710
Net proceeds from public offerings | 67,695 |
Net payment on revolving line of credit | (204) |
Proceeds from loans |  | 39,433
Repayment of debt |  | (31,010)
Net cash provided by financing activities | 68,684 | 9,133
Net (decrease) increase in cash, cash equivalents and restricted cash | (1,303) | 140
Cash, cash equivalents and restricted cash, beginning of period | 37,421 | 31,587
Cash, cash equivalents and restricted cash, end of period | $ 36,118 | $ 31,727

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