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Significant Components of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforwards | $ 141,176 | $ 135,536
Research and development credit carryforwards | 28,892 | 28,291
Capitalized research and development | 10,756 | 12,832
Compensation related items | 10,957 | 9,843
Operating leases | 4,214 | 4,374
Other | 6,051 | 4,547
Total deferred tax assets | 202,046 | 195,423
Valuation allowance | (199,042) | (192,304)
Net deferred tax assets | 3,004 | 3,119
Deferred tax liabilities: |  |
Right-of-use assets | 2,892 | 3,017
Amortization of goodwill | 163 | 143
Total deferred tax liabilities | $ 3,055 | $ 3,160

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