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Summary of Significant Accounting Policies (Tables) | 6 Months Ended
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Jun. 30, 2023
Accounting Policies [Abstract] |
Summary of Product Revenue by Geographical Locations of Customers | Product revenue by geographical locations of customers during the three and six months ended June 30, 2023 and 2022, was as follows (in thousands):
|  | Three Months Ended |  |  | Six Months Ended |
|  | June 30, |  |  | June 30, |
|  | 2023 |  |  | 2022 |  |  | 2023 |  |  | 2022 |
Product revenue: |  |  |  |  |  |  |  |  |  |  |  |
North America |  | $ | 24,477 |  |  | $ | 25,579 |  |  | $ | 41,094 |  |  | $ | 47,777 |
Europe, Middle East and Africa |  |  | 13,533 |  |  |  | 14,898 |  |  |  | 27,561 |  |  |  | 29,700 |
Other |  |  | 843 |  |  |  | 522 |  |  |  | 1,172 |  |  |  | 966 |
Total product revenue |  | $ | 38,853 |  |  | $ | 40,999 |  |  | $ | 69,827 |  |  | $ | 78,443 |
Anti-Dilutive Effect of Common Shares | The table below presents potential shares that were excluded from the calculation of the weighted average number of shares outstanding used for the calculation of diluted net loss per share. These are excluded from the calculation due to their anti-dilutive effect for the three and six months ended June 30, 2023 and 2022 (shares in thousands):
|  | Three Months Ended |  |  | Six Months Ended |
|  | June 30, |  |  | June 30, |
|  | 2023 |  |  | 2022 |  |  | 2023 |  |  | 2022 |
Weighted average number of anti-dilutive potential shares: |  |  |  |  |  |  |  |  |  |  |  |
Stock options |  |  | 14,888 |  |  |  | 16,051 |  |  |  | 15,164 |  |  |  | 15,716 |
Restricted stock units |  |  | 11,572 |  |  |  | 7,775 |  |  |  | 10,389 |  |  |  | 7,568 |
Employee stock purchase plan rights |  |  | — |  |  |  | — |  |  |  | 139 |  |  |  | 76 |
Total |  |  | 26,460 |  |  |  | 23,826 |  |  |  | 25,692 |  |  |  | 23,360 |

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- Definition Tabular disclosure of disaggregation of revenue into categories depicting how nature, amount, timing, and uncertainty of revenue and cash flows are affected by economic factor. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 606 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 5 -Publisher FASB -URI https://asc.fasb.org//1943274/2147479806/606-10-50-5 + Details
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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1 + Details
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