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Significant Components of Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforwards | $ 127,184 | $ 133,476
Research and development credit carryforwards | 29,739 | 28,567
Capitalized research and development | 35,861 | 33,571
Compensation related items | 9,437 | 10,306
Operating leases | 3,005 | 3,462
Other | 10,928 | 9,823
Total deferred tax assets | 216,154 | 219,205
Valuation allowance | (214,321) | (216,888)
Net deferred tax assets | 1,833 | 2,317
Deferred tax liabilities: |  |
Right-of-use assets | 1,676 | 2,173
Other | 226 | 209
Total deferred tax liabilities | $ 1,902 | $ 2,382

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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 740 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482685/740-10-50-2 + Details
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- Definition Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 740 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 6 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482685/740-10-50-6 + Details
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