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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Income Statement [Abstract]        
Revenue $ 0 $ 0 $ 0 $ 0
Operating expenses:        
Research and development 12,526 4,695 22,741 7,970
General and administrative 5,084 1,291 8,109 2,537
Total operating expenses 17,610 5,986 30,850 10,507
Loss from operations (17,610) (5,986) (30,850) (10,507)
Other income (expense):        
Interest income 63 1 102 1
Interest expense (213) (443) (426) (445)
Foreign currency transaction gains (losses), net 4 28 (54) 93
Total other income (expense), net (146) (414) (378) (351)
Net loss (17,756) (6,400) (31,228) (10,858)
Accretion of redeemable convertible preferred stock to redemption value   (43)   (92)
Net loss attributable to common stockholders $ (17,756) $ (6,443) $ (31,228) $ (10,950)
Net loss per share attributable to common stockholders, basic and diluted $ (0.66) $ (2.96) $ (1.19) $ (7.51)
Weighted average common shares outstanding, basic and diluted 27,011,960 2,178,465 26,316,619 1,457,931
Comprehensive loss:        
Net loss $ (17,756) $ (6,400) $ (31,228) $ (10,858)
Other comprehensive loss:        
Unrealized loss on marketable securities (21)   (25)  
Total other comprehensive loss (21)   (25)  
Total comprehensive loss $ (17,777) $ (6,400) $ (31,253) $ (10,858)