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v2.4.1.9

Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 9 Months Ended | 12 Months Ended
--- | --- | ---
Sep. 30, 2014 | Sep. 30, 2013 | Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011
Cash flows from operating activities: |  |  |  |  |
Net loss | $ (25,547)us-gaap_NetIncomeLoss | $ (10,181)us-gaap_NetIncomeLoss | $ (14,027)us-gaap_NetIncomeLoss | $ (13,880)us-gaap_NetIncomeLoss | $ (13,157)us-gaap_NetIncomeLoss
Adjustments to reconcile net loss to net cash used in operating activities |  |  |  |  |
Stock-based compensation expense | 910 us-gaap_AllocatedShareBasedCompensationExpense | 252 us-gaap_AllocatedShareBasedCompensationExpense | 395 us-gaap_AllocatedShareBasedCompensationExpense | 121 us-gaap_AllocatedShareBasedCompensationExpense | 80 us-gaap_AllocatedShareBasedCompensationExpense
Non-cash interest expense | 36 us-gaap_PaidInKindInterest |  |  | 97 us-gaap_PaidInKindInterest |
Depreciation expense | 10 us-gaap_Depreciation | 8 us-gaap_Depreciation | 12 us-gaap_Depreciation | 11 us-gaap_Depreciation | 4 us-gaap_Depreciation
Unrealized foreign currency transaction losses | 31 us-gaap_ForeignCurrencyTransactionGainLossUnrealized | 169 us-gaap_ForeignCurrencyTransactionGainLossUnrealized | 250 us-gaap_ForeignCurrencyTransactionGainLossUnrealized |  |
(Gain) loss on disposal of property and equipment |  |  |  |  | (2)us-gaap_GainLossOnSaleOfPropertyPlantEquipment
Changes in operating assets and liabilities: |  |  |  |  |
Prepaid expenses and other current assets | (997)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | 160 us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | 165 us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (269)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (61)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Tax incentive receivable | 368 us-gaap_IncreaseDecreaseInIncomeTaxesReceivable | (1,230)us-gaap_IncreaseDecreaseInIncomeTaxesReceivable | (1,237)us-gaap_IncreaseDecreaseInIncomeTaxesReceivable | (630)us-gaap_IncreaseDecreaseInIncomeTaxesReceivable |
Accounts payable | (416)us-gaap_IncreaseDecreaseInAccountsPayable | 122 us-gaap_IncreaseDecreaseInAccountsPayable | 237 us-gaap_IncreaseDecreaseInAccountsPayable | 727 us-gaap_IncreaseDecreaseInAccountsPayable | (43)us-gaap_IncreaseDecreaseInAccountsPayable
Accrued expenses | 9,078 us-gaap_IncreaseDecreaseInAccruedLiabilities | (171)us-gaap_IncreaseDecreaseInAccruedLiabilities | (799)us-gaap_IncreaseDecreaseInAccruedLiabilities | 234 us-gaap_IncreaseDecreaseInAccruedLiabilities | 905 us-gaap_IncreaseDecreaseInAccruedLiabilities
Net cash used in operating activities | (16,527)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (10,871)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (15,004)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (13,589)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (12,274)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Cash flows from investing activities: |  |  |  |  |
Purchases of property and equipment | (42)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (9)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (17)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (2)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (35)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Proceeds from sales of property and equipment |  |  |  |  | 2 us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment
Deposits for leased property | (57)us-gaap_PaymentsForDeposits |  |  |  | (12)us-gaap_PaymentsForDeposits
Net cash used in investing activities | (99)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (9)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (17)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (2)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | (45)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Cash flows from financing activities: |  |  |  |  |
Proceeds from issuance of redeemable convertible preferred stock, net of issuance costs | 442 us-gaap_ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock | 5,955 us-gaap_ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock | 40,799 us-gaap_ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock | 16,057 us-gaap_ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock | 10,069 us-gaap_ProceedsFromIssuanceOfRedeemableConvertiblePreferredStock
Issuance of convertible promissory notes, net of issuance costs | 7,386 us-gaap_ProceedsFromNotesPayable |  |  | 5,989 us-gaap_ProceedsFromNotesPayable |
Payments of debt offering costs | (49)us-gaap_PaymentsOfDebtIssuanceCosts |  |  |  |
Proceeds from exercise of common stock options |  |  |  | 13 us-gaap_ProceedsFromIssuanceOfCommonStock |
Proceeds from initial public offering costs, net of underwriting commissions and discounts | 102,672 us-gaap_ProceedsFromIssuanceInitialPublicOffering |  |  |  |
Payments of initial public offering costs | (2,312)us-gaap_PaymentsOfStockIssuanceCosts | (165)us-gaap_PaymentsOfStockIssuanceCosts | (196)us-gaap_PaymentsOfStockIssuanceCosts |  |
Net cash provided by financing activities | 108,139 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 5,790 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 40,603 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 22,059 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 10,069 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Net increase (decrease) in cash and cash equivalents | 91,513 us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | (5,090)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | 25,582 us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | 8,468 us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease | (2,250)us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease
Cash and cash equivalents at beginning of period | 35,517 us-gaap_CashAndCashEquivalentsAtCarryingValue | 9,935 us-gaap_CashAndCashEquivalentsAtCarryingValue | 9,935 us-gaap_CashAndCashEquivalentsAtCarryingValue | 1,467 us-gaap_CashAndCashEquivalentsAtCarryingValue | 3,717 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at end of period | 127,030 us-gaap_CashAndCashEquivalentsAtCarryingValue | 4,845 us-gaap_CashAndCashEquivalentsAtCarryingValue | 35,517 us-gaap_CashAndCashEquivalentsAtCarryingValue | 9,935 us-gaap_CashAndCashEquivalentsAtCarryingValue | 1,467 us-gaap_CashAndCashEquivalentsAtCarryingValue
Supplemental disclosure of non-cash investing and financing activities: |  |  |  |  |
Accretion of redeemable convertible preferred stock to redemption values | 92 us-gaap_TemporaryEquityAccretionToRedemptionValueAdjustment | 160 us-gaap_TemporaryEquityAccretionToRedemptionValueAdjustment | 213 us-gaap_TemporaryEquityAccretionToRedemptionValueAdjustment | 67 us-gaap_TemporaryEquityAccretionToRedemptionValueAdjustment | 53 us-gaap_TemporaryEquityAccretionToRedemptionValueAdjustment
Deferred offering costs and deferred financing costs included in accounts payable and accrued expenses |  | 14 us-gaap_DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction | 547 us-gaap_DebtIssuanceCostsIncurredDuringNoncashOrPartialNoncashTransaction |  |
Conversion of convertible promissory notes and accrued interest to shares of redeemable convertible preferred stock | 104,331 us-gaap_ConversionOfStockAmountConverted1 |  |  | 6,086 us-gaap_ConversionOfStockAmountConverted1 |
Supplemental disclosure of cash flow information: |  |  |  |  |
Cash paid for interest | $ 480 us-gaap_InterestPaid |  |  |  |

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