<SEC-DOCUMENT>0001193805-16-002674-index.html : 20160217
<SEC-HEADER>0001193805-16-002674.hdr.sgml : 20160217
<ACCEPTANCE-DATETIME>20160217140245
ACCESSION NUMBER:		0001193805-16-002674
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20160212
FILED AS OF DATE:		20160217
DATE AS OF CHANGE:		20160217

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ZAFGEN, INC.
		CENTRAL INDEX KEY:			0001374690
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				203857670
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		175 PORTLAND STREET
		STREET 2:		4TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02114
		BUSINESS PHONE:		617-622-4003

	MAIL ADDRESS:	
		STREET 1:		175 PORTLAND STREET
		STREET 2:		4TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02114

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ZAFGEN INC
		DATE OF NAME CHANGE:	20060906

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Deerfield Special Situations Fund, L.P.
		CENTRAL INDEX KEY:			0001354395
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36510
		FILM NUMBER:		161432625

	BUSINESS ADDRESS:	
		STREET 1:		780 3RD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		212-551-1600

	MAIL ADDRESS:	
		STREET 1:		780 3RD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Deerfield International Master Fund, L.P.
		CENTRAL INDEX KEY:			0001565089
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36510
		FILM NUMBER:		161432626

	BUSINESS ADDRESS:	
		STREET 1:		780 THIRD AVENUE, 37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		212-692-7108

	MAIL ADDRESS:	
		STREET 1:		780 THIRD AVENUE, 37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			DEERFIELD MANAGEMENT CO
		CENTRAL INDEX KEY:			0001009258
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36510
		FILM NUMBER:		161432627

	BUSINESS ADDRESS:	
		STREET 1:		780 THIRD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		2125511600

	MAIL ADDRESS:	
		STREET 1:		780 THIRD AVENUE, 37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

	FORMER NAME:	
		FORMER CONFORMED NAME:	DEERFIELD MANAGEMENT CO /NY
		DATE OF NAME CHANGE:	19981022

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			DEERFIELD PARTNERS, LP
		CENTRAL INDEX KEY:			0001301041
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36510
		FILM NUMBER:		161432628

	BUSINESS ADDRESS:	
		STREET 1:		780 THIRD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		212-551-1600

	MAIL ADDRESS:	
		STREET 1:		780 THIRD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Deerfield Mgmt L.P.
		CENTRAL INDEX KEY:			0001010823

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36510
		FILM NUMBER:		161432629

	BUSINESS ADDRESS:	
		STREET 1:		780 THIRD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		2125511600

	MAIL ADDRESS:	
		STREET 1:		780 THIRD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

	FORMER NAME:	
		FORMER CONFORMED NAME:	DEERFIELD CAPITAL LP
		DATE OF NAME CHANGE:	20050930

	FORMER NAME:	
		FORMER CONFORMED NAME:	DEERFIELD CAPITAL LP ET AL
		DATE OF NAME CHANGE:	19960318

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Flynn James E
		CENTRAL INDEX KEY:			0001352546

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36510
		FILM NUMBER:		161432630

	MAIL ADDRESS:	
		STREET 1:		780 THIRD AVENUE
		STREET 2:		37TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>e614668_4-zafgen.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
Document 1 - file: e614668_4-zafgen.html

Document 1 - RAW XML: e614668_4-zafgen.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>2
<FILENAME>e614668_ex99.htm
<TEXT>
Document 2 - file: e614668_ex99.htm

</DOCUMENT>
</SEC-DOCUMENT>