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Commitments and Contingencies - Additional Information (Detail)
 3 Months Ended 9 Months Ended
Jun. 28, 2019
Feb. 12, 2019
USD ($)
ft²
Jan. 01, 2017
ft²
Oct. 01, 2015
Apr. 15, 2015
Option
Jul. 28, 2014
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Jun. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2018
USD ($)
Other Commitments [Line Items]                      
Total lease payments over the initial term             $ 11,296,000     $ 11,296,000  
Sublease rental income             28,000     83,000  
Lease expense             374,000 $ 100,000   679,000 $ 300,000
Milestone payments due             0 $ 0   0 $ 0
Subsequent Licensed Product [Member]                      
Other Commitments [Line Items]                      
Licensing fees per product maximum             1,300,000     1,300,000  
Maximum [Member] | Pre Commercialization Milestones [Member]                      
Other Commitments [Line Items]                      
Milestone payments             12,300,000     12,300,000  
Maximum [Member] | Product Commercialization Milestones [Member]                      
Other Commitments [Line Items]                      
Milestone payments             12,500,000     12,500,000  
Research and Development [Member]                      
Other Commitments [Line Items]                      
Lease expense             200,000     500,000  
General and Administrative [Member]                      
Other Commitments [Line Items]                      
Lease expense             $ 200,000     $ 200,000  
Boston Office Space [Member]                      
Other Commitments [Line Items]                      
Lease expiration date           Jul. 31, 2020          
Amendment of lease, effective date of termination Jun. 30, 2019                    
Boston Office Space [Member] | Unrelated Third Party [Member]                      
Other Commitments [Line Items]                      
Subleased area | ft²     2,976                
Sublease expiration date     Jun. 30, 2020                
Boston Office Space [Member] | Unrelated Third Party [Member] | Scenario Forecast [Member]                      
Other Commitments [Line Items]                      
Sublease rental income                 $ 100,000    
Additional Boston Office Space [Member]                      
Other Commitments [Line Items]                      
Lease extension period         3 years            
Operating lease, existence of option to extend         true            
Lease expiration date         Jul. 31, 2020            
Number of options to extend lease | Option         1            
San Diego Office Space [Member]                      
Other Commitments [Line Items]                      
Lease expiration date       Dec. 31, 2024              
Center Plaza, Boston [Member] | Massachusetts [Member] | Shigo Center Plaza Owners LLC [Member]                      
Other Commitments [Line Items]                      
Area of office space | ft²   17,705                  
Operating lease term   124 months                  
Lease extension period   60 months                  
Letter of credit   $ 1,300,000                  
Operating lease, existence of option to extend   true                  
Total lease payments over the initial term   $ 10,700,000                  
Lease commencement date   Jun. 21, 2019