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Stockholders Equity and Stock Options - Summary of Stock Option Activity (Detail) - $ / shares
 3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Stockholders' Equity Note [Abstract]    
Number of shares, Outstanding 2,523,305  
Number of shares, Granted 600,950  
Number of shares, Forfeited/Expired 45,744  
Number of shares, Outstanding 3,078,511 2,523,305
Number of shares, Exercisable as of March 31, 2022 1,195,114  
Number of shares, Vested and expected to vest as of March 31, 2022 3,078,511  
Weighted average exercise price, balance $ 1.88  
Weighted average exercise price, Granted 8.81  
Weighted average exercise price, Forfeited/Expired 27.97  
Weighted average exercise price, balance 16.78 $ 1.88
Weighted average exercise price, Exercisable as of March 31, 2022 24.53  
Weighted average exercise price, Vested and expected to vest as of March 31, 2022 $ 16.78  
Weighted average remaining contractual term, outstanding 7 years 10 months 24 days 7 years 7 months 6 days
Weighted average remaining contractual term, Exercisable as of March 31, 2022 6 years 3 months 18 days  
Weighted average remaining contractual term, Vested and expected to vest as of March 31, 2022 7 years 10 months 24 days