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Income Taxes - Reconciliation of Federal Statutory Income Tax Rate (Detail)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Income Tax Disclosure [Abstract]    
Federal statutory income tax rate 21.00% 21.00%
State taxes, net of federal benefit 5.30% 4.90%
Change in state tax rate (1.30%) (1.70%)
Federal and state research and development tax credit 14.50% 8.20%
Nondeductible permanent differences (0.80%) (1.00%)
Stock compensation forfeitures - DTA Write Off   (1.80%)
Change in deferred tax asset valuation allowance (38.70%) (29.60%)
Effective income tax rate 0.00% 0.00%